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ProteomicsCytoskeleton-associated protein 4 (CKAP4) affects podocyte cytoskeleton dynamics in diabetic kidney disease.
Cytoskeleton-associated protein 4 (CKAP4) stabilizes the endoplasmic reticulum, by regulating its folding and anchoring to the microtubular cytoskeleton. Since podocytes are highly dependent on an intact cytoskeleton to exert their function, the role of CKAP4 was explored during normal conditions an...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD046643 | Pride
Cytoskeleton Diabetic kidney disease Integrins Podocytes Microtubules Ckap4 
ProteomicsCytoskeleton-associated protein 4 (CKAP4) affects podocyte cytoskeleton dynamics in diabetic kidney disease
Cytoskeleton-associated protein 4 (CKAP4) stabilizes the endoplasmic reticulum, by regulating its folding and anchoring to the microtubular cytoskeleton. Since podocytes are highly dependent on an intact cytoskeleton to exert their function, the role of CKAP4 was explored during normal conditions an...
ORGANISM(S): Danio Rerio (ncbitaxon:7955) 
2023-11-02 | MSV000093243 | MassIVE
ProteomicsDETECTION OF ODF1 IN KIDNEY MEDULLA
ODF1 has been described as an exclusively expressed testicular protein and is located in the outer dense fibers along the sperm tail. ODF1 has been involved in the sperm motility and in the development of the flagellum, but the function of ODF1 is not already clear. Applying western blot, immunofluo...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-05-27 | PXD014848 | Pride
Odf1 Kidney Testis 
ProteomicsBrain death associated activation of Calpain-Talin axis in donor kidneys underlies podocyte matrix degradation and graft dysfunction in kidney transplantation
Deceased kidney donation after brain death (DBD) is the main source of transplants, yet these grafts yield inferior transplant outcomes when compared to living donation. In brain death, cerebral injury contributes to systemic biological dysregulation, causing significant cellular stress in donor kid...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD022074 | Pride
Kidney cytoskeleton Podocytes Donation after brain death (dbd) Protein degradation Allograft dysfunction Kidney transplantation 
UnknownCytoskeleton-associated protein 4 affects podocyte cytoskeleton dynamics in diabetic kidney disease.
Not available
S-EPMC12288980 | biostudies-literature
GenomicsAdherent and suspension baby hamster kidney cells have a different cytoskeleton and surface receptor repertoire
Adherent and suspension baby hamster kidney cells have a different cytoskeleton and surface receptor repertoire
PRJEB44757 | ENA
TranscriptomicsAdherent and suspension baby hamster kidney cells have a different cytoskeleton and surface receptor repertoire
Animal cell culture, with single cells growing in suspension, ideally in a chemically defined environment, is the workhorse of biopharmaceutical production. The synthetic environment lacks exogenous growth factors and usually requires a time-consuming adaptation process to select cell clones that p...
ORGANISM(S): Mesocricetus auratus 
2021-05-15 | E-MTAB-10417 | biostudies-arrayexpress
TranscriptomicsEverolimus protects podocytes via stabilizing TUBB2B and DCDC2 expression
Glomerular podocytes are highly differentiated cells that are key components of the kidney filtration units. The podocyte cytoskeleton builds the basis for the dynamic podocyte cytoarchitecture and plays a central role for proper podocyte function. Recent studies implicate that immunosuppressive age...
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-66107 | biostudies-arrayexpress
UnknownRac1 promotes proximal tubule kidney repair by coupling the actin cytoskeleton to mitochondrial function.
Not available
S-EPMC12626402 | biostudies-literature
UnknownSimultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury.
Not available
S-EPMC9065033 | biostudies-literature
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