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ProteomicsCompetitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
The pluripotency transcription factor SOX2 is essential for the maintenance of glioblastoma stem cells (GSC), which drive tumor growth and treatment resistance.To understand how SOX2 is regulated in GSCs, we utilized a proteomic approach and identified the E3 ubiquitin ligase TRIM26...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD028933 | Pride
Glioblastoma Trim26 E3 ligase Wwp2 Brain cancer Sox2 
UnknownLoss of RARRES1 function Promotes Follicular Lymphomagenesis and Inhibits B cell Differentiation in Mice.
Not available
S-EPMC9066096 | biostudies-literature
TranscriptomicsExpression data of human somatic cell types and induced pluripotent stem cells
Transcription factor-mediated reprogramming yields induced pluripotent stem cells (iPSC) by erasing tissue specific methylation and re-setting DNA methylation status to an embryonic stage. We compared bona fide human iPSC derived from umbilical cord blood (CB) and neonatal keratinocytes (K). Through...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-27186 | biostudies-arrayexpress
ProteomicsCntnap2 KO mouse mPFC proteome for ASD
Autism Spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder where patients have impaired social behavior and communication, and restricted interests. Although various studies have been carried out to unveil the mechanisms associated with ASD, its pathophysiology is still poorly und...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031656 | Pride
Cntnap2 Mpfc Mouse 
UnknownAlternative Wnt Signaling Activates YAP/TAZ.
Not available
S-EPMC4538707 | biostudies-literature
TranscriptomicsDonor cell type influences the epigenome and differentiation potential of human induced pluripotent stem cells
This SuperSeries is composed of the following subset Series: GSE27134: DNA methylation data from human iPS cells, ES cells, cord blood, and keratinocytes GSE27186: Expression data of human somatic cell types and induced pluripotent stem cells GSE31742: DNA methylation data from human keratinocyte-de...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-27224 | biostudies-arrayexpress
Unknownc-Abl Kinase Targets Tight Junction Protein ZO-2 in Regulation of Cell Migration and Morphology.
Not available
S-EPMC12629166 | biostudies-literature
UnknownThe role of host DNA ligases in hepadnavirus covalently closed circular DNA formation.
Not available
S-EPMC5747486 | biostudies-literature
UnknownIdentification of an ABCB/P-glycoprotein-specific inhibitor of auxin transport by chemical genomics.
Not available
S-EPMC2906323 | biostudies-literature
ProteomicsA novel mechanism for NF-kB activation via IkB aggregation
Proteins which interact with IkBa in insoluble aggregates known as Mallory-Denk bodies were characterized by AP-MS, Biotinylation by antibody recognition (BAR), and LCMS analysis of detergent solubalized aggregates. See the supplementary table (S12) for file annotation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-31 | MSV000086042 | MassIVE
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