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MetabolomicsMechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach
S-Sulfocysteine (SSC), a bioavailable L-cysteine derivative (Cys), is known to be taken up and metabolized in Chinese hamster ovary (CHO) cells used to produce novel therapeutic biological entities. To gain a deeper mechanistic insight into the SSC biological activity and metabolization, a multi-omi...
2024-08-08 | MTBLS7424 | MetaboLights
UnknownRotenone and Its Derivative, Rotenoisin A, Induce Neurodegeneration Differentially in SH-SY5Y Cells.
Not available
S-EPMC11351421 | biostudies-literature
UnknownProtective Effect of Tat PTD-Hsp27 Fusion Protein on Tau Hyperphosphorylation Induced by Okadaic Acid in the Human Neuroblastoma Cell Line SH-SY5Y.
Not available
S-EPMC4572059 | biostudies-literature
UnknownVariability in Total Cholesterol Is Associated With the Risk of End-Stage Renal Disease: A Nationwide Population-Based Study.
Not available
S-EPMC6349220 | biostudies-literature
MetabolomicsMetabolomics-Driven Discovery of an Introduced Species and Two Malaysian Piper betle L. Variants
The differences in pungency of 'sirih' imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected M...
2022-03-21 | MTBLS2585 | MetaboLights
TranscriptomicsExpression data from Staphylococcus aureus ATCC 25923 (antibiotic sensitive) and ATCC 33591 (MRSA)
S. aureus ATCC 25923 is performance standard for antimicrobial susceptibility testing. S. aureus ATCC 33591 showed resistance against erytrhromycin, penicillin, and streptomycin. We used microarray to compare RNA expression between sensitive and resistant strain of S. aureus as a preliminary researc...
ORGANISM(S): Staphylococcus aureus 
2010-09-15 | E-GEOD-18289 | biostudies-arrayexpress
ProteomicsChemoproteomic Profiling of Reactive Cysteines in Response to Oxidative Stress Induced by 6-Hydroxydopamine
Oxidative stress is a well-known driver of neurodegeneration, yet it remains poorly understood how the global cysteine (Cys) proteome is remodeled in such conditions. Proteins with aberrantly modified Cys in response to oxidative stress can induce and exacerbate neurodegeneration. In this study, we ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD060980 | Pride
Quantitative proteomics Cell stress response Sh-sy5y Oxidative stress Neurodegeneration Neurodegenerative signaling 6-hydroxydopamine Cysteine proteomics 
UnknownLicochalcone D reduces H<sub>2</sub>O<sub>2</sub>-induced SH-SY5Y cell neurotoxicity by regulating reactive oxygen species.
Not available
S-EPMC12488560 | biostudies-literature
MetabolomicsLC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study
Today's high-resolution mass spectrometers (HRMS) allow bioanalysts to perform untargeted/global determinations that can reveal unexpected compounds or concentrations in a patient’s sample. This could be performed for preliminary diagnosis attempts when usual diagnostic processes and targeted ...
2019-06-06 | MTBLS476 | MetaboLights
ProteomicsComprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections
Streptococcus equi subspecies equi (S. equi) is a major pathogen which cause strangles, a highly contagious respiratory infection, in horses and other equines.In this study, we discovered potential vaccine candidates using comprehensive proteomics and reverse vaccinology. As the initial step, we div...
ORGANISM(S): Streptococcus equi subsp. equi 4047 
2021-08-06 | PXD025152 | Pride
Secretory proteome Label-free Membrane proteome Streptococcus equi Extracellular vesicle Whole cell lysate Lc-ms Comprehensive proteome 
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