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MetabolomicsMechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach
S-Sulfocysteine (SSC), a bioavailable L-cysteine derivative (Cys), is known to be taken up and metabolized in Chinese hamster ovary (CHO) cells used to produce novel therapeutic biological entities. To gain a deeper mechanistic insight into the SSC biological activity and metabolization, a multi-omi...
2024-08-08 | MTBLS7424 | MetaboLights
TranscriptomicsTranscription profiling of S. pneumoniae D39, a serotype 2 strain of pneumococcus, with that of an isogenic deletion mutant, (delta)luxS, time series
We were interested in determining if the LuxS signaling system contributed to the regulation of pneumococcal genes. To accomplish this, we compared the in vitro transcriptional profiles over time of S. pneumoniae D39, a serotype 2 strain of pneumococcus, with that of an isogenic deletion mutant, (d...
ORGANISM(S): Streptococcus pneumoniae 
2005-07-21 | E-SMDB-2173 | biostudies-arrayexpress
ProteomicsEpigenetic resetting in the Parkinson's disease entail histone modification remodeling.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons (DN) in the substantia nigra and disrupted cellular maintenance. Here, we demonstrate that NDST3-mediated epigenetic reprogramming halts neuronal degeneration and restores motor...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD067971 | Pride
Human Tmt Parkinson's Organoid Lc-ms/ms 
TranscriptomicsComparative genomic hybridization of 26 serovars and strains of Salmonella spp. including many representatives of subspecies I, Arizona from subsp. IIIa, and S. bongori from subsp. V
This experiment set includes 64 arrays representing 26 serovars and strains of Salmonella spp. including many representatives of subspecies I, Arizona from subsp. IIIa, and S. bongori from subsp. V. The genomic DNA from all strains were labeled with Cy5 and hybridized against an equal amount (1.5 u...
ORGANISM(S): Salmonella enterica serovar Typhimurium 
2005-09-27 | E-SMDB-1624 | biostudies-arrayexpress
TranscriptomicsATAC-seq of human GM12878 cells treated with aphidicolin and infected with Sendai virus against untreated control
ATAC-seq of human GM12878 cells to detect chromatin accessibility changes upon G1/S arrest (aphidicolin treated samples) and /or infection (Sendai virus) compared to control.
ORGANISM(S): Homo sapiens 
2025-08-27 | E-MTAB-13339 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human GM12878 and JURKAT cells treated with aphidicolin and Sendai virus against untreated controls
Human B lympoblastoid cells, GM12878 and human T cells, JURKAT, were treated with aphidicolin (to arrest cells at G1/S boundary) for 24h, the last 12h with the Sendai virus. The experiment was performed in three biological replicates. Gene expression changes upon aphidicolin and or infection betwee...
ORGANISM(S): Homo sapiens 
2025-08-27 | E-MTAB-13340 | biostudies-arrayexpress
UnknownInterprofessional communication - a concept analysis inspired by Schwartz-Barcott and Kim´s hybrid model.
Not available
S-EPMC12937564 | biostudies-literature
TranscriptomicsSingle cell RNA-seq of human GM12878 cells infected with Sendai virus and treated with aphidicolin against untreated control
Single cell RNA sequencing (scRNA-seq) of GM12878 cells upon G1/S blocker or control (DMSO) and Sendai virus infection.
ORGANISM(S): Homo sapiens 
2025-08-27 | E-MTAB-13347 | biostudies-arrayexpress
UnknownComplete mitochondrial genome of the clearwing moth <i>Synanthedon namdoelegans</i> Kim, Kim and Choi, 2025 (Lepidoptera: Sesiidae).
Not available
S-EPMC12777775 | biostudies-literature
TranscriptomicsTranscriptional reprogramming of engineered cellobiose-utilizing Saccharomyces cerevisiae in response to cellobiose revealed by RNA-Seq
Saccharomyces cerevisiae cannot metabolize cellobiose in nature. Here, S. cerevisiae was engineered to achieve cellobiose utilization by introducing both a cellodextrin transporter gene (cdt-1) and an intracellular β-glucosidase gene (gh1-1) from Neurospora crassa. We sequenced mRNA from anaerobic e...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-10 | E-GEOD-54825 | biostudies-arrayexpress
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