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MetabolomicsMetabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO)
Despite recent intensive research efforts in functional genomics, the functions of only a limited number of Arabidopsis (Arabidopsis thaliana) genes have been determined experimentally. Thus, improving gene annotation remains a major challenge in plant science. Because metabolite profiling can chara...
2014-03-01 | MTBLS47 | MetaboLights
MetabolomicsC2C12 cell line knock out SCD1 or SCD2

Lipidomic profiling was performed to compare control, SCD1-knockout, and SCD2-knockout C2C12 cells under standard culture conditions. Cell pellets were collected from routinely cultured cells, rapidly frozen, and stored at −80°C prior to lipid extraction and LC–MS/MS analysis. The study aimed to ...

2026-06-23 | MTBLS14693 | MetaboLights
MetabolomicsMuscle Clock knock out mice metabolic changes (iMSBmal1-Exp1)
Not available
ORGANISM(S): Mus musculus 
ST000313 | MetabolomicsWorkbench
MetabolomicsLooking for changes in lipid levels with knock out of ACADM (shACADM)
Not available
ORGANISM(S): Homo sapiens 
ST000771 | MetabolomicsWorkbench
MetabolomicsLooking for changes in lipid levels with knock out of ACADM (shACADM) (part II)
Not available
ORGANISM(S): Homo sapiens 
ST000819 | MetabolomicsWorkbench
ProteomicsAtxn2-Knock-Out mice show branched chain amino acids and fatty acids pathway alterations
Human Ataxin-2 (ATXN2) gene locus variants have been associated with obesity, diabetes mellitus type 1 and hypertension in genome-wide association studies, while mouse studies showed the knock-out of Atxn2 to lead to obesity, insulin resistance and dyslipidemia. Intriguingly, the deficiency of ATXN2...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-07 | MSV000084933 | MassIVE
TranscriptomicsAMPK gamma3 knock-out and mutant (R225Q) transgenic mice compared to corresponding wild type littermates
This SuperSeries is composed of the following subset Series: GSE4063: Gene expression in skeletal muscle in AMPK gamma3 knock-out mice and wild type littermates GSE4065: Gene expression in skeletal muscle in AMPK gamma3 mutant (R225Q) transgenic mice and wild type littermates. Note: GSE4063 and GSE...
ORGANISM(S): Mus musculus 
2006-02-15 | E-GEOD-4067 | biostudies-arrayexpress
ProteomicsMETTL21B is a novel human lysine methyltransferase of translation elongation factor 1A: discovery by CRISPR/Cas9 knock out
Lysine methylation is widespread on human proteins, however the enzymes that catalyse its addition remain largely unknown. This limits our capacity to study the function and regulation of this modification. Here we report that human METTL21B is a protein methyltransferase, which methylates lysine 16...
ORGANISM(S): Homo sapiens (Human) 
2017-07-03 | PXD005497 | Pride
Methyltransferase Cas9 Knockout Crispr Methylation 
ProteomicsDesmin knock-out cardiomyopathy: a heart on the verge of metabolic crisis
Background: Mutations of the desmin gene cause familial and sporadic cardiomyopathies and myopathies. Previous studies showed that both the lack of desmin and expression of mutated desmin negatively impact on number, structure and function mitochondria implying a metabolic dysfunction as disease pro...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-21 | PXD030938 | Pride
Metabolism Fatty acid Desmin Mitochondria Glucose Desminopathy Desmin knock-out Creatine kinase Cardiomyopathy Amino acid 
TranscriptomicsPhosphoglycerate mutase knock-out mutant Saccharomyces cerevisiae: physiological investigation and transcriptome analysis
Characterize the gpm1 mutant growth on dual substrate of ethanol and glycerol We used microarrays to detail the responses of the gpm1 mutant compare with reference
ORGANISM(S): Saccharomyces cerevisiae 
2011-01-24 | E-GEOD-22122 | biostudies-arrayexpress
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