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ProteomicsDIA proteomic analysis of unstimulated murine bone marrow derived macrophages from WT, Nrf2 KO and Keap1 KD cells
Unstimulated murine bone marrow derived macrophages cultured in L92 media from WT (4 biological replicates), Nrf2 KO (3 biological replicates) and Keap1 KD BMDM (3 biological replicates) were processed and analysed utilising DIA (label free) proteomic analysis. The Nrf2 KO mouse (DOI: 10.1006/bbrc.1...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-01 | PXD030455 | Pride
Dia Keap1 Nrf2 Macrophages Bmdm Murine 
TranscriptomicsMethylation of Polycomb target genes in intestinal cancer is mediated by inflammation
Using glutathione peroxidase, Gpx1 and Gpx2, double knockout (Gpx1/2-KO) mice as a model of inflammatory bowel disease predisposing to intestinal cancer, we analyzed genome-wide DNA methylation and chromatin changingM-bM-^@M-^Ys in the mouse ileum during chronic inflammation, aging and cancer. We fo...
ORGANISM(S): Mus musculus 
2008-12-31 | E-GEOD-12315 | biostudies-arrayexpress
UnknownSynaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.
Not available
S-EPMC6813971 | biostudies-literature
UnknownGDF15 is required for maintaining subcutaneous adipose tissue lipid metabolic signature.
Not available
S-EPMC11541726 | biostudies-literature
UnknownLong non-coding RNA lncMGC mediates the expression of TGF-β-induced genes in renal cells via nucleosome remodelers.
Not available
S-EPMC10266347 | biostudies-literature
UnknownAkt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model.
Not available
S-EPMC7591514 | biostudies-literature
ProteomicsBeta-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins
Previous studies have demonstrated an importance of alpha-synuclein as a modulator of various mechanisms implicated in chemical neurotransmission but information about other two synuclein family members’ involvement in molecular processes taking place in presynaptic terminals is limited. Here we dem...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD027786 | Pride
Dopamine Synapse Mptp toxicity Synuclein Transgenic mice Dopaminergic neurons Parkinson’s disease Vesicles Neurodegenerative disease Neurotransmitter vesicular uptake 
UnknownGlutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Not available
S-EPMC3291858 | biostudies-literature
UnknownMetabolic beneficial effects of targeting a long non-coding RNA, lnc-megacluster, in obesity.
Not available
S-EPMC12794071 | biostudies-literature
UnknownEmotional experiences and coping strategies of nursing and midwifery practitioners in Ghana: a qualitative study.
Not available
S-EPMC7541208 | biostudies-literature
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