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TranscriptomicsTranscriptomic analysis of E. coli aggregates reveals both a general and an adhesin-specific responses
In order to better understand bacterial aggregates mechanisms we used RNA seq and a specific setup of E. coli K12 strains expressing either the natural self-recognizing adhesin Ag43 or nanobodies based synthetic adhesins. We studied the changes in gene expression between aggregates and planktonic ce...
ORGANISM(S): Escherichia coli O17 str. K12a 
2023-12-30 | E-MTAB-11396 | biostudies-arrayexpress
TranscriptomicsRNA-seq data from healthy and DMD human cells, along skeletal muscle differentiation from induced pluripotent stem cells
3 healthy cells - 3 DMD cells - 7 time points (tissue-derived myoblasts, tissue-derived myotubes, hiPSCs, Day 3 of differentiation, Day 10 of differentiation, Day 17 of differentiation, Day 25 of differentiation) - 1 replicate per cell line for the tissue-derived samples and 3 biological replicates ...
ORGANISM(S): Homo sapiens 
2020-10-05 | E-MTAB-8321 | biostudies-arrayexpress
TranscriptomicsRNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori
Ribonucleases (RNases) are central actors in post-transcriptional regulation, a major level of regulation of gene expression in all cells. This control plays an important role in the bacterial pathogen Helicobacter pylori, although only the function of RNase J was characterized so far. Here, we stud...
ORGANISM(S): Helicobacter pylori 
2021-06-19 | E-MTAB-10045 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of PAX7+ cells isolated from injured Tibialis Anterior muscles of mice exposed to hypoxic versus normoxic atmosphere
Acute muscle injury was induced by cardiotoxin intramuscular injection in the tibialis anterior (TA) of 8-week-old Tg:Pax7nGFP mice. Mice were then housed in standard normoxic atmosphere (21%O2) or in a normobaric hypoxic chamber (10%O2), from 0 to 7 days post-injury (dpi). FACS-sorted PAX7+ (GFP+) ...
ORGANISM(S): Mus musculus 
2025-11-20 | E-MTAB-16208 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Mtfp1 KO and WT mice at the pre-symptomatic stage and at the onset of dilated cardiomyopathy
Transcriptomic analysis was performed to gain further insights into the molecular and cellular mechanisms underlying cardiac pathology.
ORGANISM(S): Mus musculus 
2021-11-25 | E-MTAB-11003 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Golden Hamster lung tissues according to sex, SARS-CoV-2 infection and treatment
Evaluating the effect of SARS-CoV-2 on the transcriptional landscape in lung tissues, assess differences relative to sex and to candidate treatment.
ORGANISM(S): Mesocricetus auratus 
2021-06-19 | E-MTAB-10128 | biostudies-arrayexpress
TranscriptomicsRNAseq data from Bacteroides thetaiotaomicron genetically modified to silence a prophage gene (RepCHP)
RNA originating from genetically modified B. thetaiotaomicron jmh43 containing the dead cas9 (dcas9) silencing construct targeting either the RepCHP gene of the Hankyphage prophage or a non-targeting guide (control). For each construct, there are three biological replicates. RNA was extracted at dif...
ORGANISM(S): Bacteroides thetaiotaomicron 
2025-12-31 | E-MTAB-14274 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of hearts from Chchd10S55L/+ and Oma1E324Q/E324Q mutant mice
Wild type (WT), Oma1E324Q/E324Q (Oma1), Chchd1055L/+ (Chchd10) and double mutant (Chchd1055L/+;Oma1E324Q/E324Q) male mice were sacrificed at 14 weeks of age and bulk RNA-seq was performed.
ORGANISM(S): Mus musculus 
2025-11-12 | E-MTAB-15305 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of hearts from Control (Yme1lLoxP/LoxP) and Yme1lHeart (Myh6-Cre; Yme1lLoxP/LoxP)
Control (Yme1lLoxP/LoxP) and Yme1lHeart (Myh6-Cre; Yme1lLoxP/LoxP) male mice were sacrificed at 35 weeks of age and bulk RNAseq was performed.
ORGANISM(S): Mus musculus 
2025-11-12 | E-MTAB-15304 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Mesocricetus auratus brainstems during Sars-CoV-2 infection (4 days post infection)
Detection of transcriptomic variations related to Covid infection in brainstems, comparing Sars-Cov-2 infected individuals with mock-infected ones considering sex as an extra parameter at 4 days post infection.
ORGANISM(S): Mesocricetus auratus 
2025-07-04 | E-MTAB-14779 | biostudies-arrayexpress
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