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UnknownHypothalamus proteomics from mouse models with obesity and anorexia reveals therapeutic targets of appetite regulation.
Not available
S-EPMC4855256 | biostudies-literature
ProteomicsFat BodFat Body, Hungry Brain: Nutriproteomics in the Hypothalamus from a Mouse Model with Obesity and Anorexiay, Hungry Brain: Nutriproteomics in the Hypothalamus from a Mouse Model with Obesity and Anorexia
Systemic acute inflammatory signals can cause profound anorexia by disrupting the physiological appetite regulation in the hypothalamic milieu. Conversely, obesity related chronic inflammation of the hypothalamus can disturb anorexigenic signals and promote abnormal body weight control. The aim of t...
ORGANISM(S): Mus musculus (Mouse) 
2018-01-29 | PXD002119 | Pride
Hypothalamus Proteomics Obesity Anorexia Acute inflammation Chronic inflammation 
ProteomicsHypothalamus proteomics from mouse models with obesity and anorexia reveals novel therapeutic targets of appetite regulation
This study examined the proteomic profile of hypothalamus in mouse models of obesity and anorexia
ORGANISM(S): Mus musculus (Mouse) 
2016-03-11 | PXD003475 | Pride
Hypothalamus Lc-ms 
UnknownCD8+ T cells in beige adipogenesis and energy homeostasis.
Not available
S-EPMC5922290 | biostudies-literature
ProteomicsDelta-like ligand 4-Notch signaling inhibition regulates pancreatic islet function and insulin secretion
Dll4-Notch signaling is required for cell fate decisions and neoplasias. However, emerging evidence suggests a role for Dll4-Notch signaling in metabolic and immune diseases. To date, there is no evidence of a direct effect of Dll4-Notch signaling inhibition on pancreatic islet function and insulin ...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-13 | PXD005333 | Pride
Gsis Dll4 Diabetes 
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