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ProteomicsProximity-dependent TurboID labeling screen on the LAMTOR complex
This proximity-dependent labeling screen was set up to investigate the “proxisome” (i.e. the sum of proteins in the labeling diameter around a bait protein) of the LAMTOR complex. Furthermore, we aimed at understanding the recruitment dynamics of known and unknown proteins to and from the LAMTOR com...
ORGANISM(S): Homo sapiens (Human) 
2026-07-10 | PXD080046 | Pride
Lc-msms Flpin-t-rex 293 cells Human Lamtor baits Embryonic kidney Turboid 
UnknownLAMTOR/Ragulator regulates lipid metabolism in macrophages and foam cell differentiation.
Not available
S-EPMC7003824 | biostudies-literature
UnknownThe lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Not available
S-EPMC10074977 | biostudies-literature
UnknownThe lysosomal LAMTOR-Rag complex functions as a checkpoint for antiviral interferon production.
Not available
S-EPMC12910037 | biostudies-literature
UnknownLAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.
Not available
S-EPMC5716276 | biostudies-literature
UnknownThe lysosomal LAMTOR-Rag complex functions as a checkpoint for antiviral interferon production
Not available
S-SCDT-10_1038-S44318-026-00695-2 | biostudies-other
UnknownThe TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex.
Not available
S-EPMC5932569 | biostudies-literature
ProteomicsThe endosomal proteome of LAMTOR2-deficient primary macrophages
A quantitative iTRAQ-based organelle proteomics analysis of endosomes derived from LAMTOR2-deficient macrophages has been performed. Primary macrophages were derived from bone marrow of conditional knockout mice carrying a specific deletion of LAMTOR2 in the monocyte/macrophage cell lineage. The com...
ORGANISM(S): Mus musculus (Mouse) 
2019-08-26 | PXD009148 | Pride
Macrophages Ragulator Organelle proteomics Lamtor Foam cells 
UnknownStructure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing.
Not available
S-EPMC10529327 | biostudies-literature
UnknownThe mechano-sensitive response of β1 integrin promotes SRC-positive late endosome recycling and activation of Yes-associated protein.
Not available
S-EPMC7521633 | biostudies-literature
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