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UnknownExpanding the clinical spectrum of B4GALT7 deficiency: homozygous p.R270C mutation with founder effect causes Larsen of Reunion Island syndrome.
Not available
S-EPMC4266744 | biostudies-literature
ProteomicsSerine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signaling
In the mammalian DNA damage response, ADP-ribosylation signaling is of crucial importance to mark sites of DNA damage as well as recruit and regulate repairs factors. Specifically, the PARP1:HPF1 complex recognizes damaged DNA and catalyzes the formation of serine-linked ADP-ribosylation marks (mono...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-05-26 | PXD036512 | Pride
Proteomics Adpr Ethcd Parp Drosophila Parg Af1521 Adp-ribosylation 
ProteomicsTargeting of Tumor Cells by the Adenovirus E4orf4 protein via Par3 Polarity Protein-Regulated Nuclear Envelope Rupture
The protein product of the Early region 4 open reading frame 4 (E4orf4) of human adenovirus 2 is reported to exhibit a tumor-selective cell killing activity. Here, we show that E4orf4’s tumoricidal activity correlated with changes in perinuclear actomyosin contractility that are controlled by an in...
ORGANISM(S): Homo sapiens (Human) 
2020-03-19 | PXD014329 | Pride
Lamin a/c Polarity proteins Actin Live cell dynamics Nuclear bleb E4orf4 
UnknownCyclosporin A monotherapy versus cyclosporin A and methotrexate combination therapy in patients with early rheumatoid arthritis: a double blind randomised placebo controlled trial.
Not available
S-EPMC1754491 | biostudies-literature
TranscriptomicsExpression data from Arabidopsis wild type and ibr1 ibr3 ibr10 triple mutant seedlings root tip segments treated with indole-3-butyric acid (IBA)
The root cap-specific conversion of the auxin precursor indole-3-butyric acid (IBA) into the main auxin indole-3-acetic acid (IAA) generates a local auxin source which subsequently modulates both the periodicity and intensity of auxin response oscillations in the root tip of Arabidopsis, and consequ...
ORGANISM(S): Arabidopsis thaliana 
2015-05-12 | E-GEOD-59426 | biostudies-arrayexpress
TranscriptomicsTranscriptomics of drougth stress in L. japonicus under normal air conditions
L. japonicus (Regel) Larsen cv, Gifu were initially obtained from Prof. Jens Stougaard
(University Aarhus, Denmark) and then self-propagated at the University of Seville.
Seeds were scarified and surface-sterilized,
germinated in 1% agar Petri dishes, and transferred to pots using a 1:1 (v/...
ORGANISM(S): Lotus japonicus 
2012-10-06 | E-MEXP-3710 | biostudies-arrayexpress
UnknownGenetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.
Not available
S-EPMC6785117 | biostudies-literature
TranscriptomicsSGEV_LRS
Comparison of genomic expression profiles in the mesenteric lymph nodes of naturally scrapie infected (clinical and preclinical stages) and control sheep. Expression profiles comparison of 7 clinical and 4 preclinical naturally scrapie infected sheep and 6 controls.
ORGANISM(S): Ovis aries 
2013-10-29 | E-MTAB-1346 | biostudies-arrayexpress
ProteomicsEngineering Af1521 macro domain increases ADP-ribose binding affinity and leads to the identification of more ADP-ribosylated proteins
Protein ADP-ribosylation is a covalent, reversible post-translational modification that has important functions in several cellular mechanisms. The identification of modified proteins in cells has proven challenging and, due to the low abundance of protein ADP-ribosylation, has mainly been possible ...
ORGANISM(S): Homo sapiens (Human) 
2020-10-20 | PXD016686 | Pride
Ap-ms Af1521 macro domain Adp-ribosylation Lc-ms/ms 
TranscriptomicsRNA sampling from a chemically diverse set of solid agar cultures of Aspergillus nidulans
In this study, we design and apply a DNA expression array for Aspergillus nidulans in combination with legacy data to form a comprehensive gene expression compendium. We apply a guilt-by-association-based analysis to predict the extent of the biosynthetic clusters for the 58 synthases active in our ...
ORGANISM(S): Emericella nidulans 
2013-04-04 | E-GEOD-39993 | biostudies-arrayexpress
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