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ProteomicsIdentifying a novel hydroxysteroid dehydrogenase enzyme that is capable of testosterone biosynthesis in the mouse
Androgens, such as testosterone and dihydrotestosterone (DHT), are essential for male sexual development, masculinisation, spermatogenesis, and general lifelong health. Androgens are predominantly synthesised in the testes of mice (~95%) by highly specialised cells known as the Leydig cells. There a...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-12 | PXD050748 | Pride
Androgens Alternate pathway Hsd17b7 Canonical pathway Testosterone Srd5a1 Testosterone biosynthesis Hsd17b3 
UnknownA universal bacteriophage T4 nanoparticle platform to design multiplex SARS-CoV-2 vaccine candidates by CRISPR engineering.
Not available
S-EPMC8442874 | biostudies-literature
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
UnknownThe role of the electroencephalogram (EEG) in determining the aetiology of psychosis: a systematic review and meta-analysis of diagnostic test accuracy.
Not available
S-EPMC7618760 | biostudies-literature
UnknownMutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with "Corner Fractures".
Not available
S-EPMC5673654 | biostudies-literature
UnknownModest functional diversity decline and pronounced composition shifts of microbial communities in a mixed waste-contaminated aquifer.
Not available
S-EPMC12036129 | biostudies-literature
UnknownMapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Not available
S-EPMC4721965 | biostudies-literature
UnknownPrevalence of diabetes in U.S. youth in 2009: the SEARCH for diabetes in youth study.
Not available
S-EPMC3898760 | biostudies-literature
UnknownAmplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy.
Not available
S-EPMC7834310 | biostudies-literature
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
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