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ProteomicsProteomic breast cancer data set for exploring somatic mutations
MCF7, SKBR3 (breast cancer) and MCF10 (non-tumorigenic) cell extracts were explored by LC-MS/MS for the identification of protein-level mutations.
ORGANISM(S): Homo sapiens (Human) 
2019-07-25 | PXD014458 | Pride
Cell lines Somatic mutations Lc-ms/ms 
ProteomicsInsulin stimulated MCF7 breast cancer cells
Proteome profile of MCF7 breast cancer cells stimulated with insulin and analyzed by nano-LC-ESI-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2016-11-30 | PXD004051 | Pride
Ms/ms 2d-scx/rplc Breast cancer Cell line 
ProteomicsProteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-deprived culture conditions
The immune functions of microglia in the brain are compromised in the presence of tumors that have the ability to “hijack” their pro-inflammatory nature by sending out signals that promote cancer progression. To analyze the tumor-supportive microglia phenotype, human microglia cells (HMC3) were trea...
ORGANISM(S): Homo sapiens (Human) 
2021-10-07 | PXD023163 | Pride
Hmc3 Cytokines Tumor Microglia 
ProteomicsProteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-enriched culture conditions
The immune functions of microglia in the brain are compromised in the presence of tumors that have the ability to “hijack” their pro-inflammatory nature by sending out signals that promote cancer progression. To analyze the tumor-supportive microglia phenotype, human microglia cells (HMC3) were trea...
ORGANISM(S): Homo sapiens (Human) 
2021-10-06 | PXD023166 | Pride
Hmc3 Cytokines Tumor Microglia 
ProteomicsShort enzymatic reactions in proteomics studies
SKBR3 breast cancer cell extracts were digested with trypsin (or LysC) on short time scales (7min, 15min, 30min, 1h, and 18h), and the results were compared to overnight digestion protocols.
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD010306 | Pride
Proteomics Mass spectrometry Fast proteolytic digestion 
UnknownAnti-inflammatory cytokine stimulation of HMC3 cells: Proteome dataset.
Not available
S-EPMC10404857 | biostudies-literature
ProteomicsProteomic analysis of human SKBR3/HER2+ breast cancer cell-surface proteins by using tryptic shaving
The plasma membrane proteome resides at the interface between the extra- and intra-cellular environment and through its various roles in signal transduction, immune recognition, nutrient transport, and cell-cell and cell-matrix interactions plays a critical role in determining the fate of a cell. Th...
ORGANISM(S): Homo sapiens (Human) 
2022-07-11 | PXD028978 | Pride
Cancer Skbr3 cells Cell-surface proteins 
ProteomicsProteomic analysis of human SKBR3/HER2+ breast cancer glycosylated cell-surface proteins
The plasma membrane proteome resides at the interface between the extra- and intra-cellular environment and through its various roles in signal transduction, immune recognition, nutrient transport, and cell-cell and cell-matrix interactions plays a critical role in determining the fate of a cell. Th...
ORGANISM(S): Homo sapiens (Human) 
2022-07-11 | PXD028976 | Pride
Cancer Glycoproteins Cell-surface Skbr3 cells 
ProteomicsProteomic analysis of human SKBR3/HER2+ breast cancer cell-surface proteins by using amine group biotinylation
The plasma membrane proteome resides at the interface between the extra- and intra-cellular environment and through its various roles in signal transduction, immune recognition, nutrient transport, and cell-cell and cell-matrix interactions plays a critical role in determining the fate of a cell. Th...
ORGANISM(S): Homo sapiens (Human) 
2022-07-11 | PXD028977 | Pride
Cancer Skbr3 cells Cell-surface proteins 
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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