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Melanoma incidence and mortality rates are historically higher for men than women. Although emerging studies have highlighted tumorigenic roles for the male sex hormone androgen and its receptor (AR) in melanoma, cellular and molecular mechanisms underlying these sex-associated discrepancies are poo...
ORGANISM(S): Homo sapiens (Human) 
2024-01-15 | PXD047337 | Pride
[1] Gene expression profiling in Gata4, Mef2a knockdown in HL-1 cells. HL-1 cells infected with adenovirus expressing either control siRNA or Gata4, and Gata4 & Mef2a siRNA. [2] Genome-wide maps of cardiac transcription factors binding region in HL-1 cells. We performed bio-ChIP-seq using streptavi...
ORGANISM(S): Mus musculus 
The zoonotic liver fluke Fasciola hepatica is responsible for economic losses to the agriculture industry worldwide. Triclabendazole has been the drug of choice. However, anthelmintic resistance is becoming prevalent with cases of resistance detected globally. This emphasizes the need for alternativ...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2026-06-29 | PXD035194 | Pride
Agilent whole exome hybridisation capture was performed on genomic DNA derived from Chondrosarcoma cancer and matched normal DNA from the same patients. Next Generation sequencing performed on the resulting exome libraries and mapped to build 37 of the human reference genome to facilitate the identi...
ORGANISM(S): Homo sapiens 
The aim of this experiment was to look at RNAs which associate with members of the closed loop complex (eIF4E, eIF4GI, eIF4GII, Pab1p) and inhibtors of the complex (Caf20p, Eap1p) under optimal growth conditions in the Saccharomyces cerevisiae BY4741 strain background. NOTE: The csfasta and qual...
ORGANISM(S): Saccharomyces Cerevisiae 
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