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ProteomicsSmall extracellular vesicles from serum (human)
Quantitative comparison of the protein load of small extracellular vesicles circulating in serum prior and after high intensity interval training.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD020330 | Pride
Small extracellular vesicle Dia Lc-ms 
ProteomicsSmall extracellular vesicles from skeletal muscle cells (human)
Quantitative comparison of the protein load of small extracellular vesicles released from human skeletal muscle cells prior and after electric pulse stimulation.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD020278 | Pride
Dia Lc-ms Human muscle cells Ev's 
ProteomicsAKT and AMPK site-specific phosphorylation on TBC1D4 biological activity
TBC1D4 is a 160 kDa multi-domain containing RabGAP (Rab GTPase-activating protein) and a downstream target of the insulin and contraction-activated kinases AKT and AMPK. While phosphorylation of TBC1D4 has been linked to GLUT4 translocation from storage vesicles (GSVs) to the cell surface, its impac...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024645 | Pride
Lc-msms Partial digest Tbc1d4 
ProteomicsThe effect of AKT and AMPK site-specific phosphorylation on TBC1D4 biological activity
TBC1D4 is a 160 kDa multi-domain containing RabGAP (Rab GTPase-activating protein) and a downstream target of the insulin and contraction-activated kinases AKT and AMPK. While phosphorylation of TBC1D4 has been linked to GLUT4 translocation from storage vesicles (GSVs) to the cell surface, its impac...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024621 | Pride
Lc-msms Tbc1d4 Protein phosphorylation 
ProteomicsSustainability of specific improvements of cardiorespiratory fitness and insulin sensitive metabolism in type 2 diabetes after exercise training
High intensity interval training (HIIT) improves metabolism, but maybe with differences in sustainability between prediabetes and type 2 diabetes (T2D). We hypothesized that HIIT-induced changes are maintained after 4-week detraining in humans with (20 T2D) and without T2D (12 insulin-sensitive, IS-...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD046654 | Pride
Exercise  detraining  insulin sensitivity  mitochondrial function  small extracellular vesicles  inter-organ crosstalk 
TranscriptomicsCytokines dominate the secretome of primary human myotubes in an in vitro exercise model
Muscle contraction during exercise is the major stimulus for the release of peptides and proteins (myokines) that are supposed to take part in the benefical adaptation to exercise. We hypothesize that application of an in vitro exercise stimulus as electric pulse stimulation (EPS) to human myotubes ...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-44051 | biostudies-arrayexpress
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