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Proteomicsbroccoli lysate treated with product of OMT1
Identification of OMT1 in broccoli through product based thermal proteome profiling
ORGANISM(S): Brassica oleracea var. botrytis (Cauliflower) 
2026-04-30 | PXD058970 | Pride
Thermal proteome profiling Omt1 Broccoli Product 
Proteomicsbroccoli lysate treated with substrate of OMT1
Identification of OMT1 in broccoli through substrate based thermal proteome profiling
ORGANISM(S): Brassica oleracea var. botrytis (Cauliflower) 
2026-04-30 | PXD058938 | Pride
Thermal proteome profiling Omt1 Broccoli Substrate 
Proteomicsmulberry lysate treated with oxyresveratrol
Identification of the biosynthetic enzyme of moracin M in mulberry through substrate based thermal proteome profiling
ORGANISM(S): Morus alba var. macroura Morus alba 
2026-04-30 | PXD058978 | Pride
Moracin m Thermal proteome profiling Oxyresveratrol Mulberry 
ProteomicsSubcellular Interactomes Revealed by Merging APEX with Cross-linking Mass Spectrometry
An integrating APEX proximity labeling and chemical cross-linking coupled with mass spectrometry (CXMS) platform named APEX-CXMS for spatially resolved subcellular interactome profiling in a high-throughput ma
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD033838 |
ProteomicsSelective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
The dual-specificity tyrosine phosphorylation-regulated kinase DYRK2 has emerged as a key regulator of cellular processes such as proteasome-mediated protein degradation. To gain further insights into its function, we took a chemical biology approach and developed C17, a potent small-molecule DYRK2 ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-26 | MSV000087106 | MassIVE
ProteomicsSelective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
The dual-specificity tyrosine phosphorylation-regulated kinase DYRK2 has emerged as a key regulator of cellular processes such as proteasome-mediated protein degradation. To gain further insights into its function, we took a chemical biology approach and developed C17, a potent small-molecule DYRK2 ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-21 | MSV000086745 | MassIVE
ProteomicsChemoproteomic profiling reveals the mechanism of bile acid tolerance in pathogens
As amphipathic molecules, BAs have strong antibacterial effects, preventing overgrowth of the gut microbiota and defending the invasion of pathogens. However, some disease-causing pathogens can survive from the BA stress and knowledge is limited about how they develop BA tolerance. In the current st...
ORGANISM(S): Escherichia Coli 
2024-10-09 | PXD056639 |
ProteomicsDDX1 Methylation Mediated MATR3 Splicing Regulates Intervertebral Disc Degeneration by Initiating Chromatin Reprogramming
Low back pain (LBP), often caused by intervertebral disc degeneration (IVDD), poses a major challenge in aging populations. DDX1, an RNA-binding protein, plays key roles in RNA metabolism but its function in IVDD remains unclear. We identify DDX1 as a non-histone substrate of lysine methyltransferas...
ORGANISM(S): Homo Sapiens 
2025-05-29 | PXD064432 |
ProteomicsConformational dynamics of the activated GLP-1 receptor-Gs complex revealed by cross-linking mass spectrometry and integrative modeling
Despite revolutionary advancements in GPCR structural biology, our understanding of the complexity of GPCR activation and signaling would not be complete without complementary information on the conformational dynamics. Yet it is particularly challenging to study the dynamics of GPCR complexes with ...
ORGANISM(S): Homo Sapiens 
2023-01-08 | PXD039315 |
ProteomicsThe proteomic change associated with EVs during their degradation
To identify the proteins within the EVs that play major roles in mediating EV sorting into lysosomes, we used a biotin-labelled method to monitor the proteomic change associated with EVs during their degradation.
ORGANISM(S): Homo Sapiens 
2025-12-06 | PXD071687 |
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