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ProteomicsThe E3 ubiquitin ligase FBXL18 stabilizes BST2 to promote inflammation in RABV-infected astrocytes
we identify the ubiquitnation sites of BST2 and used quantitative proteomic analysis to compare protein abundance between WT MA-C cells and those that have received FBXL18-specific siRNAs
ORGANISM(S): Mus musculus (Mouse) 
2025-12-29 | PXD058432 | Pride
Bst2 ubiquitination，fbxl18 proteomics 
UnknownEffects of Nitrogen Accumulation, Transportation, and Grain Nutritional Quality and Advances in Fungal Endophyte Research in Quinoa (Chenopodium quinoa Willd.) Plants.
Not available
S-EPMC11277952 | biostudies-literature
UnknownComparative profiling of 72 quinoa varieties reveals superior nutritional quality, bio-active petrochemicals, and sensory acceptability for functional leafy vegetable applications.
Not available
S-EPMC12801603 | biostudies-literature
Metabolomics4-Octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING

The Krebs cycle-derived metabolite itaconate, whose production is catalyzed by immune response gene 1 (IRG1), has excellent potential to link immunity and metabolism in activated macrophages through alkylation or competitive inhibition of target proteins. In support of this, our previous study de...

2023-01-15 | MTBLS5877 | MetaboLights
MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
ProteomicsHuman intestine LC-MSMS - Transcriptional and proteomic analysis revealed a synergistic effect of aflatoxin M1 and ochratoxin A mycotoxins on intestinal epithelial integrity of differentiated human Caco-2 cells
Aflatoxin M1 (AFM1) is a common mycotoxin in dairy milk and it is typically concurrently present with other mycotoxins that may represent a threat for food safety. However, knowledge on how AFM1, alone or in combination with other mycotoxins may affect human intestinal epithelial integrity remain to...
ORGANISM(S): Homo sapiens (Human) 
2018-08-08 | PXD009437 | Pride
Human Intestinal epithelial cells Lc-msms 
UnknownA high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value.
Not available
S-EPMC5674158 | biostudies-literature
ProteomicsAPEX2-MCM2 proximity labeling with high-resolution quantitative mass spectrometry in ESC
Through the APEX2 technique, we identified MCM2-interacting proteins associated with the replication initiation complex. After excluding proteins from the negative controls, we detected a substantial number of interacting proteins in the positive groups of both cell types. This research establishes ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD054939 | Pride
Apex2  mcm2  dna replication  proximity labeling 
ProteomicsMass spectrometry analysis of RSV-induced RAW264.7 cells
In order to further explore the expression of proteins in RSV-infected macrophages, RSV type-L19 was used to stimulate RAW264.7 cells, and then mass spectrometry was conducted to detect the expression of different proteins after RSV infection. The results showed that there were different expression ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-26 | PXD042041 | Pride
Mass spectrometry analysis Rsv Raw264.7 cells 
ProteomicsIdentification of indisulam-mediated DCAF15 interacting proteins by TurboID and shotgun proteomics
In this project, we used proximity labeling with TurboID to identify proteins that interact with DCAF15 in the presence of indisulam in a gastric cancer AGS cell line.
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD024168 | Pride
Human Ags Turboid Dcaf15 Orbitrap fusion lumos Lc-ms/ms 
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