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TranscriptomicsGene expression profiling in mature OT-II TCR transgenic CD4 SP thymocytes, either Jmjd3- and Utx-deficient or -sufficient.
The biological functions of histone demethylases Jmjd3 and Utx remain poorly understood. We assessed such functions in developing T cells, using conditional (CD4-Cre-mediated) gene disruption, by inactivating Kdm6a and Kdm6b, respectively encoding Utx and Jmjd3, in immature CD4+CD8+ thymocytes. We c...
ORGANISM(S): Mus musculus 
2015-09-17 | E-GEOD-70363 | biostudies-arrayexpress
TranscriptomicsMethylation data as part of an Integrated analysis of oligodendroglial tumours
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net: Oligodendroglial tumours (OT) are a heterogeneous group of gliomas. Three molecular subgroups are currently distinguished based on the IDH mutation and the 1p/19q co-deletion....
ORGANISM(S): Homo sapiens 
2016-03-11 | E-MTAB-3903 | biostudies-arrayexpress
TranscriptomicsFoxp1 is a rate-limiting and essential negative regulator of Tfh cell differentiation
CD4+ T follicular helper (Tfh) cells are essential for germinal center (GC) and high-affinity antibody responses. Yet the regulation that determines the initial development of Tfh cells is still largely unknown. Here we find that transcription factor Foxp1, previously shown to be essential in mainta...
ORGANISM(S): Mus musculus 
2014-05-18 | E-GEOD-50725 | biostudies-arrayexpress
ProteomicsIsotopomer analysis of quiescent primary human fibroblasts
To ensure that the pool of precursor amino acids utilized for protein synthesis is completely labeled prior to the first labeling time-point, we conducted an isotopomer analysis. After adaption to media, cells were plated at a density of 500,000 cells per 10 cm plate. 8 days after plating, the confl...
ORGANISM(S): Homo sapiens (Human) 
2016-06-14 | PXD003559 | Pride
Isotopomer analysis 15n labeling 
ProteomicsBrain proteome analysis after 6 weeks of cuprizone or normal diet and 3 weeks of 40 Hz stimlation.
Brain proteome analysis after 6 weeks of cuprizone or normal diet and 3 weeks of 40 Hz stimlation or constant light and sound (control groups).
ORGANISM(S): Mus musculus (Mouse) 
2024-06-07 | PXD044572 | Pride
Cuprizone Mouse Tmt Genus 
UnknownHighly conserved protective epitopes on influenza B viruses.
Not available
S-EPMC3538841 | biostudies-literature
ProteomicsData in support of the hPOP Human Proteomics project
A long-standing aspiration in multi-omics is to comprehensively understand how genetic and geographical factors shape phenotypic expression at the molecular, cellular and organismal level - ultimately revealing how the interplay between an organism's molecular landscape and its environment manifests...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD058813 | Pride
Proteomics Plasma Hpop Multiomics 
UnknownIdentification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure.
Not available
S-EPMC7295009 | biostudies-literature
UnknownCommon and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.
Not available
S-EPMC5951629 | biostudies-literature
UnknownGenome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
Not available
S-EPMC6326896 | biostudies-literature
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