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MetabolomicsComparative metabolomics reveals serum metabolites changes in goats during different developmental stages

Goats can provide meat, milk and skins for humans and are livestock with high economic benefits. However, despite their economic significance, the comprehensive analysis of goats' serum metabolic profile and its intricate alterations throughout their developmental journey remains conspicuously ab...

2024-06-04 | MTBLS8944 | MetaboLights
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9794 | MetaboLights
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Uterine data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9795 | MetaboLights
ProteomicsGut microbiome dysregulation is associated with elevated toxic bile acids in Parkinson’s disease
The gut microbiome can impact brain health and is altered in Parkinson’s disease (PD) patients. The vermiform appendix is a lymphoid tissue implicated in the storage and regulation of the gut microbiome. Here, we investigate changes in the functional microbiome in the appendix of PD patients relativ...
ORGANISM(S): Homo sapiens (Human) 
2021-01-28 | PXD020988 | Pride
Appendix Microbiome Gut Bile acids Parkinson’s disease 
ProteomicsCo-immunoprecipitation (Co-IP) in Nicotiana benthamiana followed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)
Ralstonia solanacearum species complex causes bacterial wilt in variety crops. Tomato cultivar Hawaii 7996 is a widely used resistance resource, however, the resistance is evaded by virulent strains with underlying mechanisms still unknown. Here, we reported that phylotype II strain ES5-1 can overco...
ORGANISM(S): Nicotiana benthamiana 
2024-07-20 | PXD054061 | Pride
Nicotiana benthamiana Ip-ms/ms 
ProteomicsMesenchymal stem cells-derived exosomes and MRC-5 cell-derived exosomes LC-MSMS
We compared the differential proteins between Mesenchymal stem cells-derived exosomes MRC-5 cell-derived exosomes.
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD033839 | Pride
Mesenchymal stem cells mrc-5 exosomes 
ProteomicsStress Granule-associated ZmCTU2 Confers Thermotolerance in Maize via Coordinated Regulation of Proteostasis and ROS Homeostasis
we performed comparative proteomic analysis of wild-type B104 and ZmCTU2-overexpressing lines. Seedlings at three-leaf-stage were grown under normal temperature condition (NC; 25°C for 12 days) and subsequently subjected to heat stress (HS; 43°C for 8 hours following NC growth). Using tandem mass ta...
ORGANISM(S): Zea Mays 
2025-12-17 | PXD072171 |
TranscriptomicsComparative transcriptome analysis of Brassica napus L. male sterility induced by the Chemical Hybridization Agent Monosulfuron Ester Sodium
Chemical hybridization agent (CHA)-induced male sterility is becoming one of the most useful tools for the crop heterosis in seed production. We had previously discovered monosulfuron ester sodium (Mes), an acetolactate synthase (ALS) inhibitor of the herbicide sulfonylurea family, could induce rape...
ORGANISM(S): Brassica napus 
2015-12-05 | E-GEOD-53468 | biostudies-arrayexpress
ProteomicsThe BPAN disease protein WDR45 forms condensates with Caprin-1 to regulate stress granule disassembly
Beta-propeller protein-associated neurodegeneration (BPAN) is a rare X-linked neurodegenerative disorder primarily caused by mutations in the WD repeat domain 45 (WDR45) gene. While WDR45 has traditionally been linked to autophagy, our study uncovers a previously unrecognized role for WDR45 as a cri...
ORGANISM(S): Homo Sapiens 
PXD062911 |
ProteomicsThe effects of Cas5 on the protein biosynthesis of Candida albicans
Cas5, a transcriptional regulator of Candida albicans, has profound effects on the biosynthesis of cell wall proteins through regulating Candida albicans cell wall remodeling
ORGANISM(S): Candida Albicans 
PXD052043 |
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