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ProteomicsMacro-porous Reversed Phase Separation of Proteins Combined with Reversed Phase Separation of Phosphopeptides and Tandem Mass Spectrometry for Profiling the Phosphoproteome of MDA-MB-231 cells
A new method of combining macro-porous reversed phase (mRP) protein fractionation with reversed phase liquid chromatography (RPLC) peptide separation tandem mass spectrometry (MS/MS) is reported for profiling the phosphoproteome of a complex sample. In this method, an mRP-C18 column was used to frac...
ORGANISM(S): Homo sapiens (Human) 
2014-07-24 | PXD000948 | Pride
Phosphoproteome Mrp-rplc Scx-rplc Mda-mb-231 Mass spectrometry 
UnknownPhysiological and Transcriptional Regulation of Salt Tolerance in <i>Thinopyrum ponticum</i> and Screening of Salt-Tolerant Candidate Genes.
Not available
S-EPMC12430373 | biostudies-literature
ProteomicsThe role of IRAKM in IL-1β-treated adipocytes
Toll-like receptors/Interleukin-1 receptor (IL-1R) signaling plays an important role in High-fat diet (HFD)-induced adipose tissue dysfunction contributing to obesity-associated metabolic syndromes. Here, we show an unconventional IL-1R-IRAKM (IL-1R-associated kinase M)-Slc25a1 signaling axis in adi...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-09 | PXD031934 | Pride
Irakm Fatty acid synthesis Pgc1a acetylation Adipocytes Slc25a1 
UnknownNew risk score for predicting progression of membranous nephropathy.
Not available
S-EPMC6368730 | biostudies-literature
TranscriptomicsacLDL-induced gene expression in wildtype and IRAK4 KI mouse macrophages
Exciting discoveries related to IL-1R/TLR signaling in development of atherosclerosis plaque have triggered intense interest in the molecular mechanisms by which innate immune signaling modulates the onset and development of atherosclerosis. Previous studies have clearly shown the definitive role o...
ORGANISM(S): Mus musculus 
2010-10-23 | E-GEOD-24894 | biostudies-arrayexpress
ProteomicsTargeting the Golgi apparatus enhances PD-L1 blockade and synergizes with oxaliplatin to improve immunotherapy efficacy
Proteomic profiling of differentially expressed proteins of 4T1 cells induced by liposome.
ORGANISM(S): Mus Musculus 
2026-02-03 | PXD073979 |
ProteomicsProteome of Klebsiella under different conditions
Changes in Klebsiella's own protein levels under different substrate treatment conditions
ORGANISM(S): Klebsiella Sp. Nccp 232 
2024-01-16 | PXD048590 |
ProteomicsSerum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis
Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis
ORGANISM(S): Homo Sapiens 
2024-03-04 | PXD050309 |
ProteomicsVAMP8 function reveals tight linkage between endocytic recycling and endocytosis
Clathrin-mediated endocytosis (CME) is a multistage process that involves the initiation and stabilization of clathrin-coated pits (CCPs) that invaginate and finally detach from the plasma membrane to form clathrin-coated vesicles (CCVs). Given that SNARE proteins are essential for downstream vesicl...
ORGANISM(S): Homo Sapiens 
2026-03-09 | PXD075425 |
ProteomicsProteomic and metabolomic signatures associated with the immune response in healthy individuals immunized with an inactivated SARS-CoV-2 vaccine
CoronaVac (Sinovac), an inactivated vaccine for SARS-CoV-2, has been widely used for immunization. However, analysis of the underlying molecular mechanisms driving CoronaVac-induced immunity is still limited. Here, we applied a systems biology approach to understand the mechanisms behind the adaptiv...
ORGANISM(S): Homo Sapiens 
2022-03-09 | PXD032127 |
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