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MetabolomicsFatty acid oxidation protects cancer cells from apoptosis through increasing mitochondrial membrane lipids

Overcoming resistance to chemotherapies remains a major unmet need for cancers such as triple negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for drug development are urgently needed to overcome TNBC therapy resistance. Recently, an important role of fatty acid β-...

2022-05-31 | MTBLS4709 | MetaboLights
UnknownReversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling.
Not available
S-EPMC10798156 | biostudies-literature
UnknownSuccinate ester derivative of δ-tocopherol enhances the protective effects against 60Co γ-ray-induced hematopoietic injury through granulocyte colony-stimulating factor induction in mice.
Not available
S-EPMC5286428 | biostudies-literature
UnknownCD226 deletion improves post-infarction healing via modulating macrophage polarization in mice.
Not available
S-EPMC7019150 | biostudies-literature
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsRegion-Resolved Proteomic Map of the Human Brain: Functional Interconnections and Neurological Implications
While progress has been made in transcriptomic profiling of the human brain, functional characterization of brain regions and their interactions based on regional protein expression remains limited. Here, we construct a proteomic map from thirteen anatomical brain regions of eight cadaver donors to ...
ORGANISM(S): Homo Sapiens 
2025-12-08 | PXD034484 |
ProteomicsO-glycosylation in fruit development and ripening
O-glycosylation is a critical post-translational modification (PTM) regulating protein function, yet its role in plant transcription factors remains poorly understood.
ORGANISM(S): Solanum Lycopersicum 
2025-12-16 | PXD072030 |
ProteomicsMass spectrometry to exam noval receptors of the The Omicron Variant of SARS-CoV-2 RBD captured by SPIDER
We used SPIDER to examine the cell-surface receptors for specific ligands while these receptors were in their native membranes within intact cells in culture. Here we coupled the SPIDER assay with biotinylated RBD of the Omicron Variant of SARS-CoV-2 and biotinylated RBD of SARS-CoV-2. Then we perfo...
ORGANISM(S): Homo Sapiens Chlorocebus Sabaeus 
2022-01-18 | PXD031035 |
ProteomicsPupylation sites on protein GFP-PupE
Characterization of GFP-Pup after Pupylation assays by mass spectrometry.
ORGANISM(S): Mycobacterium Tuberculosis H37rv_2009 
2021-06-04 | PXD026478 |
ProteomicsCheA pupylation sites identified by SPIDER assay
We used CheAs and biotin-CheZ to validate the efficiency of SPIDER capturing protein-protein interaction. Pupylation sites on WT CheAs after SPIDER assay was identified by LC-MS/MS analysis, by searching for an additional mass of ~243 Da, which represents the three C-terminal residues of Pup, i. e.,...
ORGANISM(S): Escherichia Coli 
2021-06-04 | PXD026509 |
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