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ProteomicsDiscovery of TBC1D7 as a potential driver for melanoma cell invasion.
Melanoma is a common type of cancer, and metastasis remains the leading cause for mortality in melanoma patients. In this study, we utilized an unbiased mass spectrometry-based quantitative proteomic method to assess, at the global proteome scale, differential protein expression in a matched pair of...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD014368 | Pride
Tbc1d7 Tbc domain-containing proteins Mass spectrometry Silac Melanoma metastasis Quantitative proteomics 
UnknownAdenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism.
Not available
S-EPMC7704734 | biostudies-literature
ProteomicsSaccharomyces cerevisiae LC-MSMS
IP-MS detection of proteins pulled down by Glc7-FLAG by mass spectrometry
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-10-24 | PXD036005 | Pride
Lc-msms Saccharomyces cerevisiae 
ProteomicsIP-MS detected the interation protein with PKM2
Vascular endothelial cells (ECs) senescence correlates with the increase of cardiovascular diseases in ageing population. Although ECs rely glycolysis for energy production, little is known about the role of glycolysis in ECs senescence. Here, we report a critical role for glycolysis-derived serine ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD035585 | Pride
Co-immunoprecipitation Pkm2 
ProteomicsIP-MS detected the interation proteins of PHGDH
Vascular endothelial cells (ECs) senescence correlates with the increase of cardiovascular diseases in ageing population. Although ECs rely glycolysis for energy production, little is known about the role of glycolysis in ECs senescence. Here, we report a critical role for glycolysis-derived serine ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD035586 | Pride
Mass spectrometry Phgdh Co-immunoprecipitation 
ProteomicsProteome-wide Identification of DNA Guanine Quadruplex-binding Proteins
DNA sequences of high guanine (G) content have the potential to fold into G quadruplex (G4) structures. DNA G4 is known to play important roles in various cellular processes including DNA replication, transcriptional regulation, and maintenance of genomic integrity. A more complete understanding abo...
ORGANISM(S): Homo sapiens (Human) 
2021-09-29 | PXD026794 | Pride
G-quadruplex Silac Lc-ms/ms 
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