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UnknownSpeedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization
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S-SCDT-10_1038-S44318-025-00528-8 | biostudies-other
ProteomicsDIA-Brain-aged- target gene knockout mice
The differences between wild-type mice and target gene knockout mice were analyzed by proteomic tests.
ORGANISM(S): Mus Musculus 
2025-01-13 | PXD059745 |
ProteomicsNon-invasive biomarker discovery in hereditary angioedema
Hereditary angioedema (HAE) is a rare and potentially life-threatening disease. The pathogenesis of HAE is not well understood. Moreover, non-invasive disease biomarkers are strongly needed for early diagnosis and clinical management of HAE.
ORGANISM(S): Homo Sapiens 
PXD045435 |
ProteomicsTargets identification of Danhong injection by iTSA
Proteomics data of targets identification of Danhong injection(10plex TMT)
ORGANISM(S): Homo Sapiens 
PXD052842 |
ProteomicsDIA proteomics of virgin female Schistosoma mansoni after BATT induction
Schistosomiasis, a zoonotic parasitic disease caused by trematodes of the genus Schistosoma, represents a significant zoonotic parasitic disease that affects over 200 million people across 78 countries, with a substantial burden on public health systems globally. The phenomenon of male-induced sexua...
ORGANISM(S): Schistosoma Mansoni 
PXD067676 |
ProteomicsSS18/BAFs regulate chromatin accessibility dynamics during pluripotent-somatic transition
The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of mammalian development, and is also a representative cell-fate transition model, but remains largely unresolved. Recently, we reported construction of robust JUN-induced PST completed in one cell cycle and whose ...
ORGANISM(S): Mus Musculus 
PXD029277 |
ProteomicsMouse Testis IP-MS Analysis of TEX44 Interacting Proteins
Through whole-exome sequencing of 800 patients with asthenozoospermia, we identified biallelic TEX44 variants in six individuals, all of whom exhibited defective mitochondrial sheath assembly and impaired sperm motility. Using Tex44 knockout mice, we demonstrated that TEX44 interacts with carnitine ...
ORGANISM(S): Mus Musculus 
2025-02-20 | PXD060989 |
ProteomicsSS18 regulates pluripotent-somatic transition through phase separation
The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the identification of SS18 as a regulator for pluripotent to somatic transition or PST by CRISPR-based whole genome screens. Mechanistically, SS18 forms m...
ORGANISM(S): Mus Musculus 
PXD026208 |
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