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We determine the mechanisms that control global nucleosome dynamics during embryonic stem (ES) cell differentiation into endoderm
ORGANISM(S): Mus musculus 
We determine the mechanisms that control global nucleosome dynamics during embryonic stem (ES) cell differentiation into endoderm. Three cell types (ES, pEHP, and EHP) were assayed for RNA expression levels.
ORGANISM(S): Mus musculus 
To identify the function of Senp7 in adipocytes, we conducted a pulldown aasay and mass spectrometry analysis to identify proteins that interacted with Senp7.
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD043479 | Pride
To investigate the impact of histone variants and modification on gene regulation, we report high-throughput profiles of six histone markers, H2A.Z, H3K4me2, H3K9me3, H3K27me3, H3K27ac, and H3K36me3, by ChIP-Seq in T-47D breast cancer cells. Libraries were sequenced with the Illumina HiSeq 2000 anal...
ORGANISM(S): Homo sapiens 
We report the genome-wide map of nucleosome positions in the mouse liver, with emphasis on transcriptional start sites, CpG islands, Foxa2 binding sites, and their correlation with gene expression. Despite the heterogeneity of liver tissue, we could clearly discern the nucleosome pattern of the pred...
ORGANISM(S): Mus musculus 
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease without effective medical therapies. Emerging evidences have suggested a crosstalk between adipose tissue and vascular cells and brown adipose tissue is beneficial for cardiovascular health. Nevertheless, whether brown remodeling...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-07 | PXD064197 | Pride
GwAAP: A Genome-wide Amino Acid coding-decoding quantitative Proteomic system was designed in which each protein could be assigned with a distinct code. Using synthetic biology technology, the amino acids codes were coded in N terminal of the corresponding proteins in the genome of yeast (Saccharomy...
ORGANISM(S): Saccharomyces Cerevisiae 
2021-12-22 | PXD023100 |
Abstract DNA modifications, represented by methylcytosine (5mC), and its oxidized derivatives, such as hydroxymethylcytosine (5hmC), formylcytosine (5fC), and carboxylcytosine (5caC), play important roles in epigenetic regulation of biological processes. The specific recognition of DNA modifications...
ORGANISM(S): Homo Sapiens Mus Musculus 
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