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ProteomicsProtein citrullination and homocitrullination profiling in mice using LC-MS/MS
Citrullination and homocitrullination are two post-translational modifications (PTMs) that may cause protein structural and functional changes. Although they have been linked to various biological processes and disease development, the understanding is still poor because of limitations to enrich, de...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-05 | PXD023733 | Pride
Citrullination Mouse Biotin thiol tag Homocitrullination Lc-ms/ms 
ProteomicsLC-MS/MS of different developmental stages of human pancreas
Mass spectrometry-based quantitative proteomics was used to delineate proteome-wide and extracellular matrix (ECM) alterations at four age groups in human pancreas: fetal (18-20 weeks gestation), juvenile (5-16 years old), young adults (21-29 years old) and older adults (50-61 years old).
ORGANISM(S): Homo sapiens (Human) 
2021-01-06 | PXD020130 | Pride
Human Pancreas Matrisome Developmental stages Lc-ms/ms 
UnknownFlexible Graphene Electrodes for Prolonged Dynamic ECG Monitoring.
Not available
S-EPMC5134492 | biostudies-literature
ProteomicsProteome and lipidome of Urine-derived Exosomes in Mycobacterium tuberculosis Infected Patients
This study confirmed the aberrant lipids and protein spectrum in exosomes of Mtb infected individuals, uncovered novel potential lipid biomarkers for TB/LTBI diagnosis and revealed integral role of exosomal lipid-raft-dependent biological processes in TB pathogenesis.
ORGANISM(S): Homo Sapiens 
2024-03-04 | PXD050345 |
ProteomicsExosomal proteins identification from neonatal mouse plasma
Paracrine effects mediated by exosomes contribute to the major regenerative functions of cell therapies after myocardial injuries. Early neonatal mammals retain a transient regeneration capacity after heart injury, which reminds us to explore the cardioprotective and regenerative potency of plasma e...
ORGANISM(S): Mus Musculus 
2022-12-13 | PXD038805 |
ProteomicsMechanisms underlying Florfenicol-induced stem cell toxicity using iTRAQ
iTRAQ-based proteomics was performed to explore the mechanism underlying Florfenicol-induced stem cell toxicity and assess the overall protein changes in P19SCs post FLO treatment.
ORGANISM(S): Mus Musculus 
PXD028764 |
ProteomicsThe ovarian tumor domain-containing protein 4 (OTUD4)-targeted ferroptosis inhibitor Maclekarpine E attenuates ulcerative colitis
This study aimed to evaluate the therapeutic effect of ME against UC and to elucidate its underlying molecular mechanism and potential target. ME was semi-synthesized on a gram scale via a biomimetic route. Its activity was assessed in an LPS-induced RAW264.7 macrophage model in vitro and a DSS-indu...
ORGANISM(S): Mus Musculus 
2026-01-27 | PXD073619 |
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