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UnknownApolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population.
Not available
S-EPMC4194587 | biostudies-literature
ProteomicsStomatin modulates adipogenesis through ERK pathway and regulates fatty acid uptake and lipid droplet growth
Controlling fatty acid uptake, lipid production and storage, and metabolism of lipid droplets (LDs), is closely related to lipid homeostasis, adipocyte hypertrophy and obesity. We report here that stomatin, a major constituent of lipid rafts, participates in adipogenesis and adipocyte maturation by ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-05 | PXD031866 | Pride
Erk pathway Adipogenesis 3t3-l1 adipocyte-like cell 
ProteomicsSynthetic Methylotrophic E. coli proteomics
To effectively use methanol derived from CO2 or methane in E. coli, it is crucial to develop a fast-growing strain that can efficiently process methanol. We successfully developed a methylotrophic E. coli strain, SM6, which has a doubling time of 3.5 hours, surpassing the growth rates of typical nat...
ORGANISM(S): Escherichia coli 
2024-04-24 | PXD051688 | Pride
Synthetic methylotroph Methanol Proteomics E. coli Synthetic biology 
UnknownKey Residues of Outer Membrane Protein OprI Involved in Hexamer Formation and Bacterial Susceptibility to Cationic Antimicrobial Peptides.
Not available
S-EPMC4576038 | biostudies-literature
ProteomicsProteomes of Pseudoalteromonas fuliginea BSW20308 and its Pf1 sRNA mutant at 4/32℃
To understand the functions of Pf1 sRNA in response to temperature changes, a knockout mutant (ΔPf1) was constructed. Transcriptomics and proteomics were performed on biological triplicates of the wild strain and ΔPf1 grown to stationary phase at 4°C and 32°C. The file uploaded is the original data ...
ORGANISM(S): Pseudoalteromonas sp. Bsw20308 Bacteria 
2022-12-19 | PXD036967 | Pride
Dia quantification proteomics Srna Pseudoalteromonas 
ProteomicsComparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness
O-GlcNAcylation is a reversible and dynamic post-translational protein modification catalyzed by O-GlcNAc transferase (OGT). Despite the reported association of O-GlcNAcylation with cancer metastasis, the O-GlcNAc proteome profile for cancer aggressiveness remains largely uncharac-terized. Here we r...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029627 | Pride
Lung adenocarcinoma  o-glcnac transferase  o-glcnacylation  sam68 
ProteomicsGlucosidase Alpha Neutral C Promotes Influenza Virus Replication by Inhibiting Proteosome-Dependent Degradation of Hemagglutinin
The H7N9 influenza virus poses a significant threat to human health, and the mechanism by which it infects humans remains incompletely understood. Our investigation has unveiled significant insights into the role of glucosidase alpha, neutral C (ganc) gene in human H7N9 infections. Through whole gen...
ORGANISM(S): Homo Sapiens 
2025-03-10 | PXD061732 |
ProteomicsPlasma Proteomic Changes of Atherosclerosis After Exercise in ApoE knockout Mice
Atherosclerosis is the preliminary cause of coronary artery disease, one of the diseases that ac-count for the largest number of fatal mortalities. Physical activity is an effective strategy to restrain atherosclerosis from deterioration. Evidence indicated that the changes of proteomic profile is h...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD030951 | Pride
Atherosclerosis  complement factor c5  exercise  proteomic changes  chemotaxis 
ProteomicsER-associated degradation of Eag1 potassium channels by the RING E3 ubiquitin ligase MKRN1: the presence of a dual ubiquitination system
Mutations in the human gene encoding the neuron-specific Eag1 voltage-gated K+ channel are associated with neurodevelopmental diseases, indicating an important role of Eag1 during brain development. A disease-causing Eag1 mutant channel is linked to defective protein stability that involves enhanced...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023984 | Pride
Ring e3 Mkrn1 
UnknownMetastasis-associated in colon cancer-1 in gastric cancer: Beyond metastasis.
Not available
S-EPMC4970472 | biostudies-literature
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