Sort   by:  
 Page size 
ProteomicsA click-compatible BmTyr platform for biotin-free proximity labeling and subcellular proteome profiling in primary T cells
Proximity labeling has revolutionized the study of dynamic subcellular proteomes by enabling the capture of transient protein interactions within living cells, yet the application of existing platforms to hard-to-transfect primary cells remains challenging. Here, we leverage a bioorthogonal proximit...
ORGANISM(S): Mus Musculus 
2026-05-09 | PXD078205 |
ProteomicsTargeting Pim2 Improves Effector Function and Longevity of CD8 T cells in Cancer Immunotherapy
The Pim kinase family is critically involved in tumorigenesis, yet its function in primary T cells remains poorly understood. We previously reported that Pim2 negatively regulates T-cell responses to alloantigen. To investigate how Pim2 impacts anti-tumor immunity of CD8 T cells, we generated Pim2-/...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD059837 | Pride
Pim2 T cells Cancer Immunotherapy 
TranscriptomicsExpression data from Th2 cell of ECM1 KO mice vs WT mice
CD4+ helper T cells are critical for immunological response. Th2 cells, a subset of CD4+ helper T cells, are responsible for asthma and other immune diseases. We found a Th2 secreted protein, ExtraCellular Matrix protein 1 (ECM1), which is highly induced by classic IL-4 signaling pathway during help...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-19707 | biostudies-arrayexpress
UnknownLin- PU.1dim GATA-1- defines haematopoietic stem cells with long-term multilineage reconstitution activity.
Not available
S-EPMC10623959 | biostudies-literature
ProteomicsBlocking CXCR4+ CD4+ T cells reprograms Treg-mediated immunosuppression via modulating the Rho-GTPase/NF-κB pathway
Clinical trials have demonstrated that CXCR4 antagonists enhance the efficacy of immunotherapy in cancers by reducing regulatory T (Treg) cells, elucidating how certain mechanisms of CXCR4 in affecting Treg cells are essential for developing immunotherapeutic strategies.
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058262 |
UnknownUniaxial cyclic stretch promotes osteogenic differentiation and synthesis of BMP2 in the C3H10T1/2 cells with BMP2 gene variant of rs2273073 (T/G).
Not available
S-EPMC4156358 | biostudies-literature
TranscriptomicsAcid-inducible genes in Streptococcus mutans: multiple two-component systems involved in acid adaptation
Global transcriptional analysis of acid-inducible genes in Streptococcus mutans: multiple two-component systems involved in acid adaptation pH is a major environmental factor that regulates gene expression in many bacteria. Streptococcus mutans in dental biofilms is regularly exposed to cycles of a...
ORGANISM(S): Streptococcus mutans 
2010-05-22 | E-GEOD-15125 | biostudies-arrayexpress
UnknownGadolinium-labelled iron/iron oxide core/shell nanoparticles as T 1-T 2 contrast agent for magnetic resonance imaging.
Not available
S-EPMC9083088 | biostudies-literature
ProteomicsLC-MS/MS Proteomics analysis of LncRNA SNHG6 in HEPG2 cell line
To identify the proteins interact with LncRNA SNHG6 in human cell lines, we analyzed the protein using RNA-Pulldown followed by mass spectrometry in HEPG2. We identified proteins associated with the SNHG6 sense/anti-sense in the isolated complexes using MS and searched the human databases for these ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD034782 | Pride
Lncrna Snhg6 
UnknownStaged development of long-lived T-cell receptor αβ TH17 resident memory T-cell population to Candida albicans after skin infection.
Not available
S-EPMC5943196 | biostudies-literature
Sort   by:  
 Page size