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The current experiment is a continuation of a previous study (E-MTAB-303) where spinal cords from a F2 (DAxPVG) intercross exposed to ventral root avulsion was studied. The F2 experiment revealed specific genetic regions of interest. Now, congenic lines, i.e. DA rats containing small inserts of PVG ...
ORGANISM(S): Rattus norvegicus 
The aim of the experiment is to characterize, and understand the genetics behind, the inflammatory and neurodegenerative processes occuring after ventral root avulsion (VRA), a model of spinal cord injury, by studying the genome wide expression in the injured spinal cord. We have bred an F2 intercro...
ORGANISM(S): Rattus norvegicus 
The blood-brain barrier (BBB) consists of specific physical barriers, enzymes and transporters, which together maintain the necessary extracellular environment of the central nervous system (CNS). The main physical barrier is found in the CNS endothelial cell, and depends on continuous complexes of ...
ORGANISM(S): Mus musculus 
We present an ex vivo human osteochondral model of PTOA to investigate disease effects on catabolism and cellular homeostasis in a multi-tissue system and discover biomarkers for disease progression and drug efficacy.
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD032213 | Pride
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