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TranscriptomicsDevelopment of gene expression signatures for latent and clinical tuberculosis (TB)
For further identify the differentiation between latent and clinical tuberculosis (TB), we employed whole genome microarray expression profiling to study genes with significant expression change in peripheral CD4+T cells between healthy control, latent tuberculosis (LTB) and clinical tuberculosis (T...
ORGANISM(S): Homo sapiens 
2012-08-06 | E-GEOD-27882 | biostudies-arrayexpress
UnknownScoliosis School Screening Using Electronic Devices in Henan Province, China: An Exploratory Study.
Not available
S-EPMC12743008 | biostudies-literature
ProteomicsCys-SH based quantitative redox proteomics of salt induced response in sugar beet monosomic addition line M14
Salt stress is a major abiotic stress that limits plant growth, development and productivity. Studying the molecular mechanisms of salt stress tolerance may help to enhance crop productivity. Sugar beet monosomic addition line M14 exhibits tolerance to salt stress. In this work, the changes in the ...
ORGANISM(S): Beta vulgaris subsp. vulgaris 
2021-12-30 | PXD027550 | Pride
Molecular mechanisms Sugar beet m14 line Salt stress Redox proteomics Iodotmtraq 
UnknownUnraveling heterogeneity in LUAD via multi-omics integration: molecular classification and therapeutic implications.
Not available
S-EPMC12923723 | biostudies-literature
ProteomicsAcetylation of p62 regulates base excision repair through interaction with APE1
p62, a well-known adaptor of autophagy, plays multiple functions in response to various stresses. Here, we report a function for p62 in base excision repair that is distinct from its known functions. Loss of p62 impairs BER capacity and increases the sensitivity of cancer cells to alkylating and oxi...
ORGANISM(S): Homo sapiens (Human) 
2022-07-19 | PXD034901 | Pride
Sirt7 Ape1 P62 Base excision repair Acetylation Hmof 
ProteomicsAcetylation of p62 regulates base excision repair through interaction with APE1
p62, a well-known adaptor of autophagy, plays multiple functions in response to various stresses. Here, we report a function for p62 in base excision repair that is distinct from its known functions. Loss of p62 impairs BER capacity and increases the sensitivity of cancer cells to alkylating and oxi...
ORGANISM(S): Homo sapiens (Human) 
2022-07-19 | PXD034899 | Pride
Sirt7 Ape1 P62 Base excision repair Acetylation Hmof 
UnknownStructural Characterization of Foxtail Millet (<i>Setaria italica</i>) Polysaccharides and Evaluation of Its Antioxidant and Immunostimulatory Activities.
Not available
S-EPMC11761630 | biostudies-literature
TranscriptomicshTERT promotes cell adhesion and migration independent of telomerase activity
We sequenced mRNA from 6 human cell lines stably over-expressed specific gene or empty vector, and searched for differently expressed genes after gene over-expression as compared to empty vector. mRNA levels were compared as following pairs: U2OS+hTERT vs U2OS+vector; U2OS+hTERTmut vs U2OS+vector; V...
ORGANISM(S): Homo sapiens 
2015-09-22 | E-GEOD-73277 | biostudies-arrayexpress
GenomicsDual Functions of TAF7L in Adipocyte Differentiation
The diverse transcriptional mechanisms governing cellular differentiation and development of mammalian tissue remains poorly understood. Here we report that TAF7L, a paralogue of TFIID subunit TAF7, is enriched in adipocytes and mouse white fat tissue (WAT). Depletion of TAF7L reduced adipocyte-spec...
ORGANISM(S): Mus musculus 
2013-01-07 | E-GEOD-41937 | biostudies-arrayexpress
ProteomicsProteomics reveals the potential mechanism of Mrps35 controlling Listeria intracellular proliferation in macrophages
We performed the comprehensive proteomics to analyze the dynamic expression landscape of wild type and Mrps35 Knockdown Raw264.7 cells by Listeria infection over 6h. Based on the results of mass spectrometry, we presented a wide variety of hypotheses about the mechanism of Mrps35 controlling the Lis...
ORGANISM(S): Mus Musculus 
2020-10-22 | PXD022127 |
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