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MetabolomicsMetabolic Characteristics of Schisantherin B in Mice with Metabolic-Associated Fatty Liver Disease

Objectives: To observe the pharmacokinetic differences of schisantherin B (STB) in the blood and liver of normal and metabolic-associated fatty liver disease (MAFLD) mice, as well as the changes in CYP450 enzymes in MAFLD mice. Methods: A MAFLD model was established in C57 mice fed with a high-fa...

2025-10-29 | MTBLS13232 | MetaboLights
ProteomicsPhysiological and proteomic analysis responsive mechanisms for salt stress in oat
Oat is considered as a moderately salt-tolerant crop that can be used to improve saline and alkaline soils. Previous studies have focused on short-term salt stress exposure, and the molecular mechanisms of salt tolerance in oat have not yet been elucidated. In this study, the salt-tolerant oat varie...
ORGANISM(S): Oryza Sativa 
2022-05-30 | PXD034203 |
ProteomicsGlobal Metabolomic and Lipidomic Analysis Reveal the Synergistic Effect of Bufalin in Combination with Cinobufagin against HepG2 Cells
Chansu, which is prepared from the skin secretions of toad (Bufo bufo gargarizans Cantor), is widely used in traditional Chinese medicine (TCM). Being the principal bioactive constituents of ChanSu, bufalin (BFL) and cinobufagin (CBF) have been shown to possess anticancer properties. TCM confer bioa...
ORGANISM(S): Homo sapiens (Human) 
2020-01-20 | PXD016926 | Pride
Metabolomics Bufalin Combination treatment. Lipidomics Cinobufagin 
ProteomicsIntegrative Network Analysis Reveals USP7 Haploinsufficiency Inhibits E-protein Activity in Pediatric T-lineage Acute Lymphoblastic Leukemia (T-ALL)
USP7, which encodes a deubiquitylating enzyme, is among the most frequently mutated genes in pediatric T-ALL, with somatic heterozygous loss-of-function mutations (haploinsufficiency) predominantly affecting the subgroup that has aberrant TAL1 oncogene activation. Network analysis of >200 T-ALL tran...
ORGANISM(S): Homo sapiens (Human) 
2021-03-16 | PXD023377 | Pride
Tal1 T-all Usp7 
UnknownRhizobacterium-derived diacetyl modulates plant immunity in a phosphate-dependent manner
Not available
S-SCDT-EMBOJ-2019-102602 | biostudies-other
GenomicsPCGP Histone-Capture bams - samples
DATA FILES FOR Histone Capture bams
EGAD00001000657 | EGA
GenomicsThe landscape of somatic mutations in epigenetic regulators across 1000 pediatric cancer genomes
To define the frequency and pattern of somatic mutations in epigenetic regulators in pediatric cancer, we sequenced 633 genes, encoding the majority of proteins involved in patterning the epigenome, in 1000 pediatric tumors spanning 21 different cancer subtypes. This analysis establishes an epigenet...
EGAS00001000449 | EGA
GenomicsPCGP MEL RNASEQ - samples
DATA FILES FOR PCGP SJMEL RNASEQ
EGAD00001001247 | EGA
GenomicsPCGP MEL WXS - samples
DATA FILES FOR PCGP SJMEL WXS
EGAD00001001246 | EGA
GenomicsPCGP MEL-WGS - samples
DATA FILES FOR SJMEL-WGS
EGAD00001001032 | EGA
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