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TranscriptomicsTranscription profiling of homozygous Commd1 null mouse embryos to elucidate the underlying mechanism leading to embryonic lethality
A gene expression study using microarray analysis was performed to elucidate the underlying mechanism leading to embryonic lethality in homozygous Commd1 null (Commd1-/-) mouse embryos. A gene expression profile of 9.5 dpc Commd1-/- embryos were generated and were compared to a gene expression profi...
ORGANISM(S): Mus musculus 
2006-09-01 | E-MEXP-832 | biostudies-arrayexpress
TranscriptomicsArray-based comparative genomic hybridisation analysis at 1Mb resolution of 44 pilocytic astrocytomas
Pilocytic astrocytomas (PAs), WHO Grade I, are one of the most frequently occurring childhood brain tumors. We have used microarray comparative genomic hybridization (aCGH) at 1Mb resolution to study copy number changes in a series of PAs (n=44). Single hybridization per case. 44 pilocytic astrocyto...
ORGANISM(S): Homo sapiens 
2008-04-28 | E-GEOD-11263 | biostudies-arrayexpress
ProteomicsBiochemical Foundations of Health and Energy Conservation in Hibernating Free-Ranging Subadult Brown Bear Ursus arctos
Brown bears (Ursus arctos) hibernate for 5-7 months without eating, drinking, urinating and defecating at a metabolic rate of only 25% of the summer activity rate. Nonetheless, they emerge healthy and alert in spring. We analyzed the physiological adaptations for hibernation by comparing the proteom...
ORGANISM(S): Ursus arctos arctos (European brown bear) 
2016-09-27 | PXD003946 | Pride
Ursus arctos Brown bear Proteomics Hibernation Lc-ms/ms 
UnknownBiomonitoring of per- and polyfluoroalkyl substances in minority angler communities in central New York State.
Not available
S-EPMC8715741 | biostudies-literature
ProteomicsGSK3 phosphorylation sites in Lpd
Neural crest cells are multipotent cells that delaminate from the neuroepithelium, migrating throughout the embryo. Aberrant migration causes developmental defects. Animal models are improving our understanding of neural crest anomalies, but in vivo migration behaviours are poorly understood. Here, ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-05 | PXD044150 | Pride
Gsk3 Phosphorylation Cid/etd tandem mass spectrometry Lpd 
TranscriptomicsMolecular Classification of AIDS-Related Lymphomas [including third-party data]
Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphom...
ORGANISM(S): Homo sapiens 
2012-07-17 | E-GEOD-17372 | biostudies-arrayexpress
GenomicsGlobal Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II
We developed a novel approach to isolate and characterize, at nucleotide-level resolution, the RNAs derived from RNA polymerase II (Pol II) in early elongation complexes. We find that high numbers of these short RNAs are not correlated with gene expression but instead are indicative of promoter-prox...
ORGANISM(S): Drosophila melanogaster 
2009-12-11 | E-GEOD-18643 | biostudies-arrayexpress
TranscriptomicsMolecular Classification of AIDS-Related Lymphomas
Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphom...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-GEOD-17189 | biostudies-arrayexpress
TranscriptomicsComparison of RNA-Seq and Microarray in Transcriptome Profiling During T Cell Activation
Samples in this study probe the gene expression kinetics in human CCR6+ Th17 memory T cells activated under Th17 condition. Human CCR6+ Th17 memory T cells were purified from PBMC and gene expression was studied over a time course of 3 days after activation under Th17 condition. RNA from these samp...
ORGANISM(S): Homo sapiens 
2014-03-11 | E-GEOD-48978 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of genes impacted by 5 day knockdown of SLC24A5 in normal human melanocytes.
A major development in pigmentation research was the discovery of the involvement of SLC24A5 in natural variation in skin colour. This study used Agilent whole-genome microarrays to examine the impact of SLC24A5 knockdown on the transcriptome of normal human melanocytes derived from lightly and dark...
ORGANISM(S): Homo sapiens 
2012-04-25 | E-GEOD-21565 | biostudies-arrayexpress
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