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ProteomicsMass Spectrum-based Identification of direct-binding proteins of TAIII-probe
This experiment utilizes a technology platform based on the Ultimate 3000 nano ultra-high-performance liquid chromatography coupled with the Q Exactive Plus high-resolution mass spectrometer, combined with database search software, to perform qualitative (or relative quantitative) analysis of protei...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD060766 | Pride
ProteomicsHeme-activated Promiscuous Targeting of Artemisinin in Plasmodium falciparum
Plasmodium falciparum, the most pathogenic human malaria parasite, infects millions of human beings and causes a serious public health threat. Currently, the most potent anti-malarial drugs are artemisinin and its derivatives1,2. Artemisinin is a sesquiterpene lactone with an endoperoxide bridge3. T...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2015-12-17 | PXD002611 | Pride
Mechanism of action Target Artemisinin Chemical proteomics 
UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
GenomicsH2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation
Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show that H2A.Z is highly enriched at promoters and enhancers and is required for both efficient self-renewa...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-34483 | biostudies-arrayexpress
ProteomicsStable Coordination Unlocks Ligand-accelerated Transition Metal Catalysis on Proteins
This project investigates in situ deprotection reactions catalyzed by the Ni–BCS system in MC38 cells and the subsequent impact on the immunopeptidome. Two independent MC38 cell preparations (2 × 10⁷ cells each) were pulsed with either the P2 peptide or P2 peptide followed by Ni–BCS catalyzed in sit...
ORGANISM(S): Mus Musculus 
2025-09-02 | PXD067964 |
ProteomicsTargeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
The efficacy of immunotherapy against colorectal cancer (CRC) is impaired by insufficient immune cell recruitment into the tumor microenvironment. Our study shows that targeting circDNA2v, a circular RNA commonly overexpressed in CRC, can be exploited to elicit cytotoxic T-cell recruitment. CircDNA2...
ORGANISM(S): Homo Sapiens 
2024-04-11 | PXD051359 |
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