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UnknownSystems pharmacology approaches decipher the anti-cancer efficacy of ethnopharmacological agents in hepatocellular carcinoma.
Not available
S-EPMC12711885 | biostudies-literature
ProteomicsCombining transcriptome and proteome analysis to identify and characterize the RpoS regulon in Pseudomonas fluorescens
Background: Microorganisms are the major cause of food spoilage during storage, processing and distribution. Pseudomonas fluorescens is a typical spoilage bacterium that contributes to a large extent to the spoilage process of proteinaceous food. RpoS is considered an important global regulator invo...
ORGANISM(S): Pseudomonas fluorescens 
2019-11-12 | PXD010845 | Pride
Transcriptome Pseudomonas fluorescens Rpos Proteome Regulon 
UnknownA MF-ConvLSTM-XAI model integrating multi-feature and fuzzy control for financial time series forecasting.
Not available
S-EPMC12669620 | biostudies-literature
ProteomicsAutomated MagNet Enrichment Unlocks Deep and Cost-Effective LC-MS Plasma Proteomics
Plasma is an ideal material for proteomics due to its diverse protein content reflecting physiological and pathological states, and its compatibility with minimally invasive sampling. Deep proteomic profiling of plasma is limited by high-abundant proteins that mask the detection of low-abundant prot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-05 | MSV000097796 | MassIVE
ProteomicsThe changes of Proteomeand Protein Phosphorylation reveals the protective roles of exogenous nitrogen in alleviating cadmium toxicityin poplar plants
Phytoremediation soil polluted by heavy metal has been drawn on a worldwide attention from human society. However, how to improve the efficiency of plant remediation of soil contaminated by cadmium remains unknown. Previous studies showed that nitrogen (N) significantly enhanced cadmium uptake in po...
ORGANISM(S): Populus yunnanensis 
2020-05-26 | PXD013360 | Pride
Plants Exogenous nitrogen Phosphorylation 
ProteomicsThe Role of CDYL-Regulated Crotonylation of RPA1 in Homologous Recombination-Mediated DNA Repair
Lysine crotonylation (Kcr) is a recently-identified protein short-chain acylation. We have previously reported that chromodomain Y-like transcription corepressor CDYL acts as a crotonyl-CoA hydratase and negatively regulates histone Kcr. However, the global crotonylome of CDYL-regulated Kcr on non-h...
ORGANISM(S): Homo sapiens (Human) 
2020-04-02 | PXD013616 | Pride
Cdyl crotonylation  rpa1 dna repair 
ProteomicsLoss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella
Aberrant sperm flagella impair sperm motility and cause male infertility, yet the genes which have been identified in multiple morphological abnormalities of the flagella (MMAF) can only explain the pathogenic mechanisms of MMAF in a small number of cases. Here, we identify and functionally characte...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD011730 | Pride
Mutation Sperm flagella Morphological abnormalities Proteomics analysis 
ProteomicsAlterations of human plasma proteome profile on adaptation to high-altitude hypobaric hypoxia
For individuals migrating to or residing permanently at high-altitude regions, environmental hypobaric hypoxia is a primary challenge which induces several physiological or pathological responses. It is well documented that human beings adapt to hypobaric hypoxia via some protective mechanisms, such...
ORGANISM(S): Homo sapiens (Human) 
2019-03-27 | PXD012221 | Pride
Proteomics  high altitude  hypobaric hypoxia  complement and coagulation cascades  antioxidant  glycolysis. 
ProteomicsProteomic analysis of lysine acetylation provides strong evidence for involvement of acetylated histone and chloroplast proteins in CWMV infected plant
Protein lysine acetylation (Kac) is an important post-translational modification (PTM) mechanism in both eukaryotes and prokaryotes, with key roles in cellular regulation. To investigate the role of Kac in plants infected with virus, we characterized the lysine acetylome of Nicotiana benthamiana pla...
ORGANISM(S): Nicotiana tabacum (Common tobacco) 
2021-05-07 | PXD012537 | Pride
Lysine acetylation Cwmv Photosynthesis Histone h3 Chloroplast 
ProteomicsPBP inactivation and OXA treatment resulted in altered protein compositions of Staphylococcal membrane vesicles
The engineered Staphylococcus aureus strain RN4220Δagr/EDⅢ was treated with 1/4 MIC of Oxacillin (OXA), or used to construct pbp3 and pbp4 gene mutant strain. Then, the membrane vesicles (MVs) of parent strain (ΔagrMVs), OXA-treated strain (Δagr/OXAMVs), and pbp3/pbp4 mutants (Δagr/OXAMVs) were harv...
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Rn4220 
PXD057038 |
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