Sort   by:  
 Page size 
ProteomicsGasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway
Pancreatic ductal adenocarcinoma (PDAC) originates from normal pancreatic ducts where digestive juice is regularly produced. It remains unclear how PDAC can escape auto-digestion by digestive enzymes. Here we show that human PDAC tumor cells use gasdermin E (GSDME), a pore-forming protein upon caspa...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD030879 | Pride
Gsdme，pancreatic ductal adenocarcinoma，ybx1 Mucin 
ProteomicsDifferences in proteins between normal and asthmatic mice and effects of knockout TL1A on asthmatic mice
Asthma, a heterogeneous disease, is characterized by chronic inflammation, epithelial–mesenchymal transformation (EMT), and airway remodeling. After immune system activation, macrophages, T cells, and other cells gather and secrete various factors, such as interleukin-1β, 4, 5, 10, 13, and TNF-a, wh...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD031079 | Pride
Asthma Tl1a Emt Ova Airway remodeling Tnf-a 
ProteomicsProteomics detection of mouse embryonic 17.5 dpc cultured ovaries in vitro
In this project, the ovaries of mice at 17.5 dpc embryonic stage were collected, and KN93, an inhibitor of CAMKII, and IWP2, an inhibitor of Wnt5a, were added for in vitro culture. Proteins affected by KN93 and IWP2, which were regulated by CAMKII and Wnt5a, were detected by proteomics technology, s...
ORGANISM(S): Mus Musculus 
2022-07-07 | PXD035136 |
Sort   by:  
 Page size