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TranscriptomicsIn vivo polarization of Ovalbumin (OVA)-specific CD4 (OTII) T cells
There remains a need for analysis of CD4 helper T cells differentiation in vivo. To this end ovalbumin (OVA)-specific CD4 (OTII) T cells transferred into congenic mice were studied. Live attenuated OVA-expressing Salmonella (SalOVA) induce T-bet and IFN-g in OTII cells, while alum-precipitated OVA (...
ORGANISM(S): Mus musculus 
2008-06-27 | E-GEOD-7481 | biostudies-arrayexpress
TranscriptomicsmiR-21 OVA Lung
Lungs from miR-21+/+ and miR-21-/- mice sensitized with OVA/Alum and challenged with either saline or OVA.
ORGANISM(S): Mus musculus 
2011-08-25 | E-MEXP-3119 | biostudies-arrayexpress
ProteomicsThe Serpin-like Loop-insertion of Ovalbumin Increases Stability and Reduces OVA 323-339 Epitope Immunogenicity
Chicken ovalbumin (cOVA) has been studied for decades primarily due to the robust genetic and molecular resources that are available for experimental investigations. cOVA is a member of the serpin superfamily of proteins that function as protease inhibitors, although cOVA does not exhibit this activ...
ORGANISM(S): Gallus gallus (Chicken) 
2021-05-07 | PXD021756 | Pride
Lc-ms Antigen processing Limited proteolysis 
ProteomicsOVA N-glycans PGC-LC-MSMS - Large-scale identification and visualization of N-glycans with primary structures using GlySeeker
With PNGase F digestion, PGC enrichment,OVA N-glycans were analyzed using PGC nanoLC-ESI-MS/MS.Datasets were analyzed by the N-glycan database search engine called GlycanGoggle developed in our group.
ORGANISM(S): Gallus gallus (Chicken) 
2019-01-17 | PXD006400 | Pride
Pgc-lc-msms Ova N-glycans 
ProteomicsANR DeepProt : A structural analysis of heated Ovalbumin by crosslink proteomics
In the present study, we mobilized the latest methodologies in tandem mass spectrometry and cross-link proteomics to decipher the heat-induced structural changes of OVA in the presence or absence of sugar. Our objective was to better understand how these structural changes could lead to a modulation...
ORGANISM(S): Gallus gallus (Chicken) 
2023-04-13 | PXD030366 | Pride
Glycation Ova Crosslink proteomics Aggregation 
TranscriptomicsGene expression changes in C57Bl/6 and CD16-/- murine bone-marrow derived dendritic cells (BMDCs) following overnight stimulation with OVA or OVA-immune complex
Atopic asthma is a chronic inflammatory disease of the lungs that is commonly associated with a Th2 response. The role of allergen-specific IgG in the initiation and development of allergic airway inflammation is still poorly understood; however, a receptor of IgG-immune complexes, CD16, has been de...
ORGANISM(S): Mus musculus 
2013-02-20 | E-GEOD-44388 | biostudies-arrayexpress
TranscriptomicsProfiling whole lung from Ovalbumin (OVA)-challenged and control BALB/c mice
This program aims at identifying the lung gene signature associated with OVA-challenged mouse asthma model to facilitate understanding of the disease mechanism and therapeutic compound testing The OVA-challenged profiling data was analyzed by identifying genes that were up- and down-regulated at sel...
ORGANISM(S): Mus musculus 
2013-03-22 | E-GEOD-31949 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse lungs, exposed in-utero to second-hand smoke (SHS) and challenged with ovalbumin (OVA) as adults.
SHS exposure during pregnancy has adverse effects on offspring. We used microarrays to characterize the gene expression changes caused by in-utero SHS exposure and adult (19-23 weeks) OVA challenge in 23-week mouse lungs. Left lungs from Balb/c male and female mice were collected at 23 weeks of age ...
ORGANISM(S): Mus musculus 
2012-06-01 | E-GEOD-38409 | biostudies-arrayexpress
TranscriptomicsThe role of aquaporin-3 (AQP3) in functions of alveolar macrophage (AM) during ovalbumin (OVA)-induced asthma
We compared the gene expression profiles of AMs using microarray analysis between AMs from wild-type (WT) and AQP3-deficient (AQP3-/-) mice before and after OVA challenge RNA was extracted from AMs of WT and AQP3-/- mice before and after OVA challenge. We prepared 4-6 mice for each group and pooled ...
ORGANISM(S): Mus musculus 
2015-04-30 | E-GEOD-68420 | biostudies-arrayexpress
ProteomicsDIA rawdata of OVA and Mogroside V
total DIA rawdata of OVA and Mogroside V,assigned to 3 groups total of 9 documents.
ORGANISM(S): Mus Musculus 
2021-11-10 | PXD029664 |
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