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This is a dataset generated by the modENCODE Project. It contains both the pair-end and single-end sequencing data of genomic DNA, chromatin input and the ChIP of the factors Su(Hw) and H3K36me3 from Drosophila S2 cells and it was generated on Illumina Genome Analyzer. The goal was to sequence ~120M...
ORGANISM(S): Drosophila melanogaster 
Diarrheal disease is a common health problem with complex causality. Although diarrhea is accompanied by disturbances in microbial diversity, how gut microbes are involved in the occurrence of diarrhea remains largely unknown. Here, using a pig model of post-weaning stress-induced diarrhea, we aim t...
2023-01-09 | MTBLS4040 | MetaboLights
We showed that with genetic manipulation as Pten/Socs3 knockout (KO), CNTF overexpression and Lipin1 knockdown (PSCL), RGCs could regenerate and reinnervate into OPN nuclei after pre-OPN optic tract injury. We then performed single-cell RNA sequencing on OPN-projecting retinal ganglion cells and pro...
ORGANISM(S): Mus Musculus 
Exposure to high-altitude hypoxic environments may lead to dysfunction in the central nervous system. Research on the hypoxic response mechanisms of hypoxia-tolerant animals can provide insights for animal conservation and the treatment of ischemic brain injury. In this study, we focused on Brandt's...
ORGANISM(S): Lasiopodomys Brandtii 
KDM1A requires an adaptor protein with specific DNA-binding activity to recognize chromatin sequence. We constructed HepG2 cells stably overexpressing KDM1A-Flag tag using lentivirus. We performed Co-IP with Flag-gel and we used LC-MS to determine the immunoprecipitates of KDM1A.
ORGANISM(S): Homo Sapiens 
DIA proteomic analysis of temp induced VBNC Bartonella henselae
ORGANISM(S): Bartonella Henselae Str. Houston-1 
A rabbit CAS provocation model was established to screen potential diagnostic biomarkers using quantitative serum proteomics
ORGANISM(S): Oryctolagus Cuniculus 
Immunoprecipitation coupled with mass spectrometry (IP/MS) was performed in HaCaT cells using an anti-B7-H3 antibody to identify B7-H3-interacting proteins. Raw mass spectrometry data are provided.
ORGANISM(S): Homo Sapiens 
For the GST pull-down of DRG ganglion, the GST- or Tmc7-GST-associated beads were further incubated with cell lysates derived from DRG ganglion. The pulled-down proteins were then separated by SDS-PAGE gel electrophoresis and subsequently stained with silver staining Kit. Finally, the target molecul...
ORGANISM(S): Mus Musculus 
2024-03-08 | PXD050466 |
Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone (FSH). Though POI affects many aspects of women’s health, its major causes remain unknown. Many clinical studies have shown that POI pati...
ORGANISM(S): Homo Sapiens 
2022-10-13 | PXD037353 |
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