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ProteomicsUBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice
For proteomics analysis, testes of Ube2j2-/- and WT mice were collected on ice, washed once with pre-cooled PBS, dried with absorbent paper, and immediately placed in liquid nitrogen, dry ice, or at -80 ℃. Samples were packed in dry ice and transported to Hangzhou Jingjie Biotechnology Company (PTM ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-05 | PXD063637 | Pride
Meiosis arrest Synaptonemal complex disassembly. Ube2j2 Homologous recombination 
ProteomicsIntegrated proteomic and Metabolomic analysis to study the effects of spaceflight on Candida albicans
Background: Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study,we aim to explore the phenotypic changes and possible mechanisms of Candida albicans after exposure to spac...
ORGANISM(S): Candida Albicans 
2020-08-27 | PXD016983 |
UnknownBacterial Changes in Boiled Crayfish between Different Storage Periods and Characterizations of the Specific Spoilage Bacteria.
Not available
S-EPMC10453257 | biostudies-literature
ProteomicsEffect of spaceflight on the phenotype and proteome of Escherichia coli
BACKGROUND: Microbial safety has become a research hotspot with the development of manned space technology. Escherichia coli is a conditional pathogen that can cause infectious diseases. Therefore, it is necessary to study the influence of space environment on Escherichia coli. METHODS: Phenotypic e...
ORGANISM(S): Escherichia Coli 
2020-12-16 | PXD023158 |
ProteomicsProteomics analysis of Polyphyllin D-treated triple-negative breast cancer cells reveal the anticancer mechanisms of Polyphyllin D
Polyphyllin D (PD) is the active component from an Asian traditional medicinal herb Paris polyphylla, and has been found to hold significant anticancer activity in vivo or in vitro. However, the mechanism through which PD exerts its anticancer effects in triple-negative breast cancer (TNBC) remains ...
ORGANISM(S): Homo Sapiens 
2023-03-20 | PXD040990 |
ProteomicsYKT6 is essential for male fertility by promoting meiosis progression through vesicular transport regulation during spermatogenesis of mice
The tetraploid spermatocytes of postnatal days (PD) 16 Ykt6-Ctrl and Ykt6-cKO mice obtained by fluorescence-activated cell sorting were subjected to proteomics analysis. After three rinses with phosphate-buffered saline (PBS), the samples were gathered into tubes containing lysis buffer, flash froze...
ORGANISM(S): Mus Musculus 
2025-04-22 | PXD063213 |
ProteomicsProteomics of intestine in simulated microgravity rats
After 14 days simulated microgravity，rats jejunal mucosa was taken for proteomic study. A total of 1826 proteins were detected, and 335 differentially expressed proteins were detected, of which 190 were up-regulated and 145 were down-regulated.
ORGANISM(S): Rattus Norvegicus 
2020-09-17 | PXD021522 |
ProteomicsMulti-Omics of Spinal Ependymal Tumor
We conducted a multi-omics analysis of 25 patients, comprising 8 with ependymoma, 10 with myxopapillary ependymoma, and 7 with subependymoma, to identify both shared and distinct genomic, transcriptional, and proteomic features among these subtypes.
ORGANISM(S): Homo Sapiens 
2024-09-20 | PXD056112 |
ProteomicsLysine methylation promotes NFAT5 activation upon EGFR activation and predicts response to temozolomide
Temozolomide (TMZ) therapy offers minimal clinical benefits in patients with glioblastoma multiforme (GBM) with high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of...
ORGANISM(S): Homo Sapiens 
2022-11-01 | PXD037869 |
ProteomicsMulti-organ Proteomic and Phosphoproteomic Profiles of Mpox Virus Infection in SIVmac239-infected Rhesus Macaques
Macaque study was conducted in an ABSL-3 facility, adhering to protocols approved by the Institutional Animal Care and Use Committee (IACUC) under the guidelines of the Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (Approval Number XJ23004). All animals were single-hous...
ORGANISM(S): Macaca Mulatta 
2024-10-12 | PXD056753 |
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