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RNAPII is responsible for transcription of protein-coding genes and short, regulatory RNAs. In Saccharomyces cerevisiae, termination of RNAPII-transcribed RNAs ≤1000 bases requires the NNS complex (comprised of Nrd1, Nab3, and Sen1) processing by the exosome, and the nuclear specific catalytic subun...
ORGANISM(S): Saccharomyces cerevisiae 
Mapping of SARS-CoV-2 (D614G) cysteine disulfides with treatment of benzylthiol-based reducting agents
ORGANISM(S): Homo sapiens (Human) 
2022-01-27 | PXD030783 | Pride
Creatine supplementation is widely used in sports and increasingly popular among exercising individuals. Although the physiological role of creatine has been extensively studied, the creatine biology in pathological status remains poorly understood. Here we report that exogenous creatine supplementa...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-27 | PXD065649 | Pride
The advent of high-throughput measurements of gene expression and bioinformatics analysis methods offers new ways to study gene expression patterns. The primary goal of this study was to determine the time sequence for gene expression in a bone subjected to mechanical loading, during key periods of...
ORGANISM(S): Rattus norvegicus 
Genome-wide DNA methylation profiles of SGI-110-treated ovarian cancer xenografts were obtained using next generation Illumina Infinium 450k assay which includes over 450,000 GpG sites. DNA from 6 samples were hybridized to the Illumina's Infinium HumanMethylation 450 BeadChip
ORGANISM(S): Homo sapiens 
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