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ProteomicsA small-molecule inhibitor targeting AKR1C1 suppresses cell proliferation and metastasis in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by highly invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis and has gained attention as an anticancer dru...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD031082 | Pride
Alantolactone  akr1c1  anticancer  target identification  non-small cell lung cancer 
UnknownIncreased expression of EZH2 indicates aggressive potential of urothelial carcinoma of the bladder in a Chinese population.
Not available
S-EPMC6290761 | biostudies-literature
ProteomicsIdentification of circEZH2_005-interacting proteins by mass spectrometry
liquid chromatography tandem mass spectrometry is used to identificate of the circEZH2_005-Interacting protein pulled down by circEZH2_005 junction probe with protein extracts from Intestinal crypt cells.
ORGANISM(S): Mus Musculus 
2023-03-17 | PXD040925 |
ProteomicsIntegrated tissue proteome and metabolome reveal key elements and regulatory pathways in cutaneous squamous cell carcinoma
we took advantage of nanoscale liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (nanoLC/Q-TOF-MS/MS) and ultraperformance LC/Q-TOF-MS/MS techniques on cancer and the corresponding paracancerous tissues from 20 CSCC patients for integrated proteomic and metabolomic analyse...
ORGANISM(S): Homo Sapiens 
2021-01-20 | PXD023716 |
ProteomicsIntegrative Comparative Proteomics Identifies Core Differentially Expressed Proteins and Pathways for Drought Tolerance by Exploiting Contrasting Rice Varieties
More tightly coordinated response was revealed at the protein level in the tolerant varieties by proteomic analysis. Carbohydrate metabolism, redox homeostasis and protein transport were found activated in the tolerant varieties in functional enrichment analysis; while photosynthesis was suppressed....
ORGANISM(S): Oryza Sativa 
2026-01-11 | PXD072923 |
ProteomicsAnalyze the post-translation modification of UVRAG
To explore the role of post-translational modification on UVRAG, we used tandem mass spectrometry (MS/MS) to analyze the UVRAG from cells.
ORGANISM(S): Homo Sapiens 
2022-06-14 | PXD034521 |
ProteomicsMass spectrometric profiling of intermolecular disulfide bonds between ROMO1 and its targets
Mass spectrometric profiling of intermolecular disulfide bonds between ROMO1 and its targets
ORGANISM(S): Homo Sapiens 
2024-06-11 | PXD053027 |
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