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UnknownA comprehensive study on non-governmental actors in shaping grassland ecological compensation within legal frameworks.
Not available
S-EPMC10917782 | biostudies-literature
ProteomicsThe deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
Spermiogenesis defines the final phase of male germ cell differentiation. Multiple deubiquitinating enzymes have been linked to spermiogenesis, yet the impacts of deubiquitination on spermiogenesis remain poorly characterized. Here, we investigated the function of UAF1 in mouse spermiogenesis and ma...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-07 | PXD046120 | Pride
Uaf1 usp1 male infertility spermiogenesis deubiquitylation 
ProteomicsBioorthogonal Photocatalytic Proximity Labeling in Primary Living Samples
In situ profiling of subcellular proteomic networks in primary and living systems, such as primary cells from native tissues or clinic samples, is crucial for the understanding of life processes and diseases, yet challenging for the current proximity labeling methods (e.g., BioID, APEX) due to their...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-05-24 | PXD045791 | Pride
Proximity labeling Mitochondria Bioorthogonal chemistry Photocatalysis 
UnknownDevelopment and validation of a nomogram for predicting the risk of malignancy in intraductal papillary neoplasms: a retrospective study.
Not available
S-EPMC12639384 | biostudies-literature
MetabolomicsBlood pseudotargeted metabolome of moyamoya disease

We aimed to identify specific metabolomic changes and biomarkers for the differential clinical diagnosis of different subtypes of moyamoya disease (MMD). We conducted an pseudotargeted metabolomics analysis and pseudotargeted metabolomics analysis revealed decreased LPC expression in patients wit...

2024-10-31 | MTBLS10304 | MetaboLights
ProteomicsYKT6 is essential for male fertility by promoting meiosis progression through vesicular transport regulation during spermatogenesis of mice
The tetraploid spermatocytes of postnatal days (PD) 16 Ykt6-Ctrl and Ykt6-cKO mice obtained by fluorescence-activated cell sorting were subjected to proteomics analysis. After three rinses with phosphate-buffered saline (PBS), the samples were gathered into tubes containing lysis buffer, flash froze...
ORGANISM(S): Mus Musculus 
PXD063213 |
ProteomicsTransgenic mice with myeloid-specific overexpression of human S100A12
S100A12, a newly discovered member of the S100 family of calcium regulatory proteins, is located within the same gene cluster on chromosome 1q21 as other S100A family members. In humans, S100A12 is mainly secreted by neutrophils and monocytes, but can also be expressed by tissue cells, such as mucos...
ORGANISM(S): Mus <genus> 
2025-01-25 | PXD060232 |
ProteomicsProteins interacting with GBP5 and RSV-SH protein
HEK293T were transfected with RSV-SH-HA, GBP5-HA or VR1012(empty vector) respectively for 48 h and then harvested. Co-IP assay were performed with HA beads (Roche, catalog no. 11867423001), the elution was analyzed by mass spectrum. Mass spectrum analysis were performed by the national center for pr...
ORGANISM(S): Homo Sapiens 
PXD054621 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD020653 |
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