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ProteomicsStudying the role of LMTK3 in the brain
Studying the phosphorylation events related to LMTK3 and its associated proteins in the brain. LMTK3 appears to be associated with the excitatory and inhibitory synaptic machinery, therefore this study was carried out to examine it's role in modulating inhibitory synapses.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-05-22 | PXD050212 | Pride
Synapse Phosphorylation Gaba Mouse Lmtk3 Brain 
ProteomicsLMTK3 inhibition affects microtubule stability
Elucidating the global proteomic alterations in MCF7 breast cancer cells, following pharmacological inhibition of LMTK3 using the C28 inhibitor
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024644 | Pride
Breast cancer Nusap1 Kinase inhibitor Tubulin Lmtk3 
GenomicsLMTK3 Represses Tumour Suppressor-Like Genes through Chromatin Remodeling in Breast Cancer
LMTK3 is an oncogenic receptor tyrosine kinase (RTK) implicated in various types of cancer including breast, lung, gastric and colorectal. It is localized in different cellular compartments but its nuclear function has not been investigated thus far. We have mapped LMTK3 binding across the genome us...
ORGANISM(S): Homo sapiens 
2015-06-30 | E-GEOD-70385 | biostudies-arrayexpress
ProteomicsLMTK3 Represses Tumour Suppressor-Like Genes through Chromatin Remodeling in Breast Cancer
LMTK3 is an oncogenic receptor tyrosine kinase (RTK) implicated in various types of cancer including breast, lung, gastric and colorectal. It is localized in different cellular compartments but its nuclear function has not been investigated thus far. We have mapped LMTK3 binding across the genome us...
ORGANISM(S): Homo sapiens (Human) 
2019-10-30 | PXD002399 | Pride
Lmtk3 chromatin breast cancer 
GenomicsLMTK3 Represses Tumour Suppressor-Like Genes through Chromatin Remodeling in Breast Cancer
LMTK3 is an oncogenic receptor tyrosine kinase (RTK) implicated in various types of cancer including breast, lung, gastric and colorectal. It is localized in different cellular compartments but its nuclear function has not been investigated thus far. We have mapped LMTK3 binding across the genome us...
ORGANISM(S): Homo sapiens 
2015-06-30 | GSE70385 | GEO
ProteomicsIdentification of LMTK3 protein by LC/MS/MS Analysis of 1D SDS PAGE Gel Bands
Identification of LMTK3 by LC/MS/MS. A plasmid encoding for full-length LMTK3 was overexpressed in MCF-7 breast cancer cells. Following antibody detection by WB, two bands of interest were seen at around 200 kDa and 150 kDa on the blotting membrane. Colloidal Coomassie (CCBB) staining was performed ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD001004 | Pride
Silac Lmtk3 Breast cancer Integrin b1 Grb2 
UnknownThe structure-function relationship of oncogenic LMTK3.
Not available
S-EPMC7673765 | biostudies-literature
UnknownLMTK3 confers chemo-resistance in breast cancer.
Not available
S-EPMC5992129 | biostudies-literature
UnknownLMTK3 promotes tumorigenesis in bladder cancer via the ERK/MAPK pathway.
Not available
S-EPMC7530379 | biostudies-literature
UnknownThe Inhibitory Properties of a Novel, Selective LMTK3 Kinase Inhibitor.
Not available
S-EPMC9821308 | biostudies-literature
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