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TranscriptomicsMicroRNA-674-5p/5-LO axis is important in concanavalin A-induced acute mouse liver injury
Eight-week-old male pathogen-free BALB/c mice were used for the induction of concanavalin A (Con A)-induced hepatitis. Animals were acclimated for at least 6-7 days to a 12-hour light/dark cycle in a humidity- and temperature-controlled, specific-pathogen-free environment in autoclaved cages. Mice w...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-76345 | biostudies-arrayexpress
ProteomicsPhosphoproteome of Hepatitis C Virus infected Huh7.5.1 cells
This project enriched and identified phosphoproteins in human hepatocarcinoma 7.5.1 cell line (Huh7.5.1) upon Hepatitis C virus (HCV) infection.
ORGANISM(S): Homo sapiens (Human) Recombinant Hepatitis C virus J6/JFH1-J6 
2016-07-08 | PXD000988 | Pride
Hepatitis c virus Phosphoproteome 
TranscriptomicsTranscription profiling of human umbilical cord blood and adult bone marrow CD34+CD33-CD38-Rho(lo)c-kit+ cells to identify candidate regulators of HSC self-renewal versus differentiation fate decisions
The global gene expression profiles of human umbilical cord blood and adult bone marrow CD34+CD33-CD38-Rho(lo)c-kit+ cells, enriched for hematopoietic stem/progenitor cells (HSC) with CD34+CD33-CD38-Rho(hi) cells, enriched in committed hematopoietic progenitor cells (HPC), were compared to identify ...
ORGANISM(S): Homo sapiens 
2007-10-30 | E-GEOD-2666 | biostudies-arrayexpress
TranscriptomicsActivating c-KIT mutations confers oncogenic cooperativity and rescue RUNX1-ETO induced DNA-damage in human cells
REtr causes genomic instability in U937 cells. Activated forms of c-KIT, like c-KIT(N822K), rescues the Retr induced genomic instability by increasing the rate of DNA repair by homologous recombination Human U937 cells were transduced with retroviral vectors encoding REtr or c-KIT(N822K), expanded i...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-57658 | biostudies-arrayexpress
TranscriptomicsGeneration and purification of Th1 and Th2 effector and memory CD4+ T cells
Naïve CD4+ T cells were isolated from spleen of AND TcR transgenic/green fluorescence protein (GFP) transgenic mice (Kaye et al., Nature 1989;341:746, Wright et al, Blood 2001;97:2278) that recognize a peptide of pigeon cytochrome C in the context of I-Ek and express CD44lo, CD62Lhi, CD45RBhi, and ...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-8352 | biostudies-arrayexpress
ProteomicsExploring CD26-/lo subpopulations of lymphocytes in asthma phenotype and severity: a novel CD4+ T cell subset expressing archetypical granulocyte proteins.
Different naïve or memory cell subpopulations (i.e., central memory/CM, effector memory/EM, or terminally differentiated effector memory/EMRA) are involved in asthma development, and they display variable levels of the CD26 (dipeptidyl peptidase 4/DPP4). The phenotype and/or severity of the disease ...
ORGANISM(S): Homo sapiens (Human) 
2025-02-17 | PXD051222 | Pride
Clustering Asthma Effector memory T helper Cd26 Lymphocytes 
UnknownHuman CD34(lo)CD133(lo) fetal liver cells support the expansion of human CD34(hi)CD133(hi) hematopoietic stem cells.
Not available
S-EPMC5037276 | biostudies-literature
UnknownComparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils.
Not available
S-EPMC6097673 | biostudies-literature
ProteomicsA neuropeptide regulates cell non-autonomous protein homeostasis
The coordination of protein homeostasis from the brain to periphery is essential for the health and survival of all animals. In C. elegans, glia serve a central role in coordinating organismal protein homeostasis and longevity via the unfolded protein response of the endoplasmic reticulum (UPRER). H...
ORGANISM(S): Caenorhabditis elegans 
2026-03-09 | PXD062951 | Pride
Neuropeptide C. elegans Upr Proteostasis 
TranscriptomicsTranscription profiling of mouse lymph node cells after immunizaion with pigeon cytochrome C B10.BR mice
Mice were immunized with PCC (pigeon cytochrome c). Experiment Overall Design: Lymph node cells were isolated by flow cytometry at successive timepoints after immunization for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7548 | biostudies-arrayexpress
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