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TranscriptomicsEpigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation
Background: Late gestational sleep fragmentation (LG-SF) is one of the major perturbations associated with sleep apnea and other sleep disorders during pregnancy. Objectives: To investigate the effects of late LG-SF on the epigenome of visceral white adipose tissue (VWAT) in the offspring. Methods: ...
ORGANISM(S): Mus musculus 
2015-04-02 | E-GEOD-63208 | biostudies-arrayexpress
TranscriptomicsSleep in a dish: key electrophysiological, molecular, and metabolic signatures of sleep and wakefulness revealed in primary cortical cultures
Although at the organismal level sleep is defined as a behavioral state, at the level of the cerebral cortex sleep has a distinct local and use-dependent aspect. This observation raises the question whether sleep is a functional property of a complex brain or occurs at the level of neuronal assembli...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-33491 | biostudies-arrayexpress
GenomicsBDNF/TrkB and local sleep
BDNF-TrkB signaling orchestrates the buildup process for local sleep
PRJEB66436 | ENA
GenomicsBDNF/TrkB and local sleep
BDNF-TrkB signaling orchestrates the buildup process for local sleep
PRJEB66435 | ENA
ProteomicsBDNF-TrkB signaling orchestrates the buildup process for local sleep
Using pharmacology and optogenetics perturbations, we showed that cortical brain-derived neurotrophic factor (BDNF) regulates the intensity of SWA via the activation of Tyrosine kinase B (TrkB) receptor and cAMP-response element-binding protein (CREB). We identified that the circuitry mediating TrkB...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-22 | PXD045652 | Pride
Circadian Bdnf Sleep homeostasis Creb Trkb Local sleep 
ProteomicsIdentifying altered mouse gephyrin interactome after sleep deprivation
GABAergic transmission controls cortical sleep, however the molecular determinants of GABAergic control of this phenomenon are unknown. We used immunoprecipitation of the inhibitory postsynaptic protein gephyrin to identify gephyrin interactors at ZT6 (sleep) and ZT6 with sleep deprivation (ZT6SD).
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD048929 | Pride
Mouse Gephyrin interactome Sleep deprivation 
UnknownHeritability and genetic correlations for sleep apnea, insomnia, and hypersomnia in a large clinical biobank.
Not available
S-EPMC11031312 | biostudies-literature
UnknownSleep Apnea and Cardiovascular Disease: Lessons From Recent Trials and Need for Team Science.
Not available
S-EPMC5689452 | biostudies-literature
UnknownNovel non-invasive assessment of upper airway inflammation in obstructive sleep apnea using positron emission tomography/magnetic resonance imaging.
Not available
S-EPMC8881562 | biostudies-literature
UnknownAssociations of daily weather and ambient air pollution with objectively assessed sleep duration and fragmentation: a prospective cohort study.
Not available
S-EPMC7669563 | biostudies-literature
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