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ProteomicsHighly Multiplex Targeted Proteomics Enabled by Real-Time Chromatographic Alignment
Targeted mass spectrometry methods produce high quality quantitative data in terms of limits of detection and dynamic range, at the cost of a substantial compromise in throughput compared to methods such as data independent and data de-pendent acquisition. The logistical and experimental issues inhe...
ORGANISM(S): Homo Sapiens 
2021-01-24 | PXD018675 | panorama
ProteomicsGIGANTEA interaction proteomics time course
Interaction proteomics time course over 24h every 4h, looking for novel interactors of the circadian clock and flowering time protein GIGANTEA. Plants expressing 35S:GIGANTEA:3xFlag6His were used, as well as WT plants for a background control.
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2017-07-03 | MSV000081217 | MassIVE
UnknownMultiple N-of-1 trials to investigate hypoxia therapy in Parkinson's disease: study rationale and protocol.
Not available
S-EPMC9281145 | biostudies-literature
UnknownTrajectories and Transitions in Service Use Among Older Veterans at High Risk of Long-Term Institutional Care.
Not available
S-EPMC11545584 | biostudies-literature
TranscriptomicsSystems Toxicology Identifies Mechanistic Impacts of 2-amino-4,6-dinitrotoluene (2-ADNT) Exposure in Northern Bobwhite
A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to pursue a holistic understanding of the effects of the explosives degradation product 2-amino-4,6-dinitrotoluene (2A-DNT) dosing on the health of the wildlife bird model, Northern bobwhi...
ORGANISM(S): Colinus virginianus 
2015-07-01 | E-GEOD-59910 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Schistosoma mansoni larval development using serial analysis of gene expression (SAGE)
Biomphalaria glabrata infection by the Schistosoma mansoni free-swimming miracidium and its subsequent development to the parasitic sporocyst stage is critical to establishment of viable infections and triggers a variety of physiological, biochemical and molecular changes. Here, we describe a genom...
ORGANISM(S): Schistosoma mansoni 
2009-03-09 | E-GEOD-9722 | biostudies-arrayexpress
ProteomicsBONCAT enables time-resolved analysis of protein synthesis in native plant tissue
Pulsing the non-canonical amino acid azidohomoalanine into Arabidopsis thaliana seedlings enables in-gel visualization, physical enrichment, and identification of newly synthesized proteins.
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2017-07-03 | PXD005577 | JPOST Repository
MetabolomicsA conserved metabolic signature associated with response to fast-acting antimalarial agents

Characterizing the mode of action of antimalarial compounds that emerge from high-throughput phenotypic screens is central to understanding how parasite resistance to these drugs can emerge. Here, we have employed untargeted metabolomics to inform on the mechanism of action of antimalarial leads ...

2023-09-27 | MTBLS6580 | MetaboLights
UnknownStrategies for correcting very long chain acyl-CoA dehydrogenase deficiency.
Not available
S-EPMC4400356 | biostudies-literature
ProteomicsUSP18 interactor and PTM mass spectrometry
The ubiquitin-like protein ISG15 is activated in response to type 1 interferons and its conjugation to proteins regulates the response to bacterial and viral infection. Its subsequent deconjugation, by a single human enzyme, USP18, critically controls interferon signaling and the defense against pat...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD058618 | Pride
Usp41 Isg15 Deisgylation Deubiquitinase Usp18 
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