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TranscriptomicsTranscription profiling of human whole blood from pediatric septic shock patients
In an ongoing translational research program involving microarray-based expression profiles in pediatric septic shock, we have now conducted longitudinal studies focused on the temporal expression profiles of canonical signaling pathways and gene networks. Genome-level expression profiles were gener...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8121 | biostudies-arrayexpress
GenomicsPositioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (RNA-Seq)
Positioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (RNA-Seq)
PRJNA1184756 | ENA
OtherPositioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (CLIP-Seq)
Spermatozoid’s flagella assemble in transcriptionally silent spermatids and thus depends on post-transcriptional regulation of gene expression. Mutations in Nsun7 gene are known to cause male infertility in human and mice. We identified m5C-specific Nsun7 RNA methyltransferase as a protein present i...
ORGANISM(S): Mus musculus 
2025-04-23 | GSE281899 | GEO
TranscriptomicsPositioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (RNA-Seq)
Spermatozoid’s flagella assemble in transcriptionally silent spermatids and thus depends on post-transcriptional regulation of gene expression. Mutations in Nsun7 gene are known to cause male infertility in human and mice. We identified m5C-specific Nsun7 RNA methyltransferase as a protein present i...
ORGANISM(S): Mus musculus 
2025-04-23 | GSE281586 | GEO
GenomicsPositioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (CLIP-Seq)
Positioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (CLIP-Seq)
PRJNA1186158 | ENA
Methylation profilingPositioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (BS-RNA-Seq)
Spermatozoid’s flagella assemble in transcriptionally silent spermatids and thus depends on post-transcriptional regulation of gene expression. Mutations in Nsun7 gene are known to cause male infertility in human and mice. We identified m5C-specific Nsun7 RNA methyltransferase as a protein present i...
ORGANISM(S): Mus musculus 
2025-04-23 | GSE281866 | GEO
GenomicsPositioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (BS-RNA-Seq)
Positioning of sperm tail longitudinal columns depend on Nsun7, an RNA binding protein destabilizing elongated spermatid transcripts (BS-RNA-Seq)
PRJNA1186075 | ENA
ProteomicsProteome of wild type and Nsun7 knockout mice spermatozoa
Investigation of a new RNA-modification-based mechanism in mammalian spermatogenesis. We created a mice line devoid of testis-specific m5C RNA methyltransferase Nsun7. These mice demonstrated male infertility due to a peculiar defect in sperm tail assembly – mispositioning of the longitudinal column...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD067410 | Pride
Spermatozoa Nsun7 Spermatogenesis Longitudinal columns Methyltransferase 
ProteomicsProteome of wild type and Nsun7 knockout mice testis
Investigation of a new RNA-modification-based mechanism in mammalian spermatogenesis. We created a mice line devoid of testis-specific m5C RNA methyltransferase Nsun7. These mice demonstrated male infertility due to a peculiar defect in sperm tail assembly – mispositioning of the longitudinal column...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-07 | PXD057007 | Pride
Testis Nsun7 Spermatogenesis Longitudinal columns Methyltransferase 
ProteomicsProteome of wild type and Nsun7 knockout mice round spermatids
Investigation of a new RNA-modification-based mechanism in mammalian spermatogenesis. We created a mice line devoid of testis-specific m5C RNA methyltransferase Nsun7. These mice demonstrated male infertility due to a peculiar defect in sperm tail assembly – mispositioning of the longitudinal column...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD067398 | Pride
Nsun7 Spermatogenesis Round spermatids Longitudinal columns Methyltransferase 
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