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TranscriptomicsZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes
Histone acetylation, including acetylated H3K14 (H3K14ac), is generally linked to gene activation. Monomethylated histone H3 lysine 4 (H3K4me1), together with other gene-activating marks, denotes active genes. In contrast to usual gene-activating functions of H3K14ac and H3K4me1, we here show that t...
ORGANISM(S): Homo sapiens 
2016-07-28 | E-GEOD-82260 | biostudies-arrayexpress
ProteomicsPrenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities
The bactericidal function of neutrophils are dependent on myriad intrinsic and extrinsic stimuli. Using systems immunology approaches we identified microbiome- and infection-induced changes in neutrophils. We focused on investigating the Prenylcysteine oxidase 1 like (Pcyox1l) protein function. Muri...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-14 | PXD031115 | Pride
Neutrophil Prenylation Pcyox1l 
UnknownPhase II study of everolimus and letrozole in patients with recurrent endometrial carcinoma.
Not available
S-EPMC4348638 | biostudies-literature
TranscriptomicsTranscriptome of rice seedling and callus based on RNA-seq method
To support our research of epigenomics in rice genome, we conducted massively parallel pyrosequencing of mRNAs (RNA-seq) using rice seedling and callus tissues. We obtained a total of 40.1 M reads from seedling and 29.6 M reads from callus.The RNA-seq data derived from the replicates showed high cor...
ORGANISM(S): Oryza sativa Japonica Group 
2011-11-09 | E-GEOD-33265 | biostudies-arrayexpress
GenomicsBase-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics
5-methylcytosine (5mC), the predominant epigenetic modification on DNA, plays critical roles in mammalian development and is dysregulated in various human pathologies. In mammals, the TET family of dioxygenases can oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5...
ORGANISM(S): Mus musculus 
2015-01-20 | E-GEOD-56429 | biostudies-arrayexpress
UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
UnknownChemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.
Not available
S-EPMC4322257 | biostudies-literature
UnknownLymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.
Not available
S-EPMC5455597 | biostudies-literature
UnknownYthdf2-mediated m6A mRNA clearance modulates neural development in mice.
Not available
S-EPMC5984442 | biostudies-literature
UnknownEarly Activation of Lung CD8<sup>+</sup> T Cells After Immunization with Live <i>Plasmodium berghei</i> Malaria Sporozoites.
Not available
S-EPMC11888604 | biostudies-literature
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