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ProteomicsExploring the early molecular pathogenesis of osteoarthritis using differential network analysis of human synovial fluid
This MS data set was used as validation data for an exploratory proteomics study of biomarkers in osteoarthritis (OA) using SOMAscan assay data. We analyzed human synovial fluid from three groups with the two methods: 1) deceased donors with mildly degenerated cartilage and/or meniscus, which is a w...
ORGANISM(S): Homo sapiens (Human) 
2024-05-13 | PXD051182 | Pride
Human Osteoarthritis Synovial fluid 
UnknownDoes tattoo exposure increase the risk of cutaneous melanoma? A population-based case-control study.
Not available
S-EPMC12756314 | biostudies-literature
ProteomicsGlycoproteomic and phenotypic elucidation of B4GALNT2 expression variants in the SID histo-blood group system
The Sda histo-blood group antigen [GalNAcβ1-4(NeuAcα2-3)Galβ-R] is present in colon, kidney and body fluids among 96-98% of Europeans whilst 90% have Sda-positive erythrocytes. Sda is implicated in various infections and constitutes a potential biomarker for colon cancer. The 2-4% truly Sd(a‒) indiv...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD023943 | Pride
Glycosylation Flow cytometry Glycopeptide Glycobiology Glycoprotein Sid blood group system Carbohydrate biosynthesis Erythrocyte Gene expression Glycosyltransferase 
UnknownAlkali-Stable Anion Exchange Membranes Based on Poly(xanthene).
Not available
S-EPMC9850910 | biostudies-literature
UnknownSoil organic carbon storage in a mountain permafrost area of Central Asia (High Altai, Russia).
Not available
S-EPMC8497679 | biostudies-literature
TranscriptomicsDNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status
We assessed DNA methylation and copy number status of 27,000 CpGs in 149 urothelial carcinomas and integrated the findings with gene expression and mutation data. Methylation was associated with gene expression for 1,332 CpGs, of which 26% showed positive correlation with expression, i.e., high meth...
ORGANISM(S): Homo sapiens 
2012-08-31 | E-GEOD-33510 | biostudies-arrayexpress
UnknownTransition from saliva droplets to solid aerosols in the context of COVID-19 spreading.
Not available
S-EPMC8459388 | biostudies-literature
TranscriptomicsSpatially restricted position-dependent implications of lamin A promoter occupancy on gene activity (ChIPs and MeDips)
Interactions between the nuclear lamina (NL) and chromatin are thought to occur through large lamin association domains (LADs) and correlate with gene repression in these domains. We show that binding of lamin A/C (LMNA) to promoters occurs on discrete domains that are associated with distinct trans...
ORGANISM(S): Homo sapiens 
2013-07-14 | E-GEOD-42522 | biostudies-arrayexpress
ProteomicsPseudouridylation of tRNA-derived fragments steers translational control in stem cells
Pseudouridylation (Ψ) is the most abundant and widespread type of RNA epigenetic modification in living organisms; however, the biological role of Ψ remains poorly understood. Here, we show that a Ψ-driven posttranscriptional program steers translation control to impact stem cell commitment during e...
ORGANISM(S): Homo sapiens (Human) 
2018-04-11 | PXD008676 | Pride
Dimethyl labelling Trna Pseudouridylation 
UnknownStructural Characterization of Covalently Stabilized Human Cystatin C Oligomers.
Not available
S-EPMC7461555 | biostudies-literature
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