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TranscriptomicsMre11 suppresses replication stress and gene amplification proficiency
Gene amplification, copy-number increases of particular genes and surrounding genomic segments, promotes cancer progression and acquired therapy resistance. Thus, understanding genetic traits that confer gene amplification proficiency is important. The primary step for gene amplification is sponta...
ORGANISM(S): Cricetulus griseus 
2015-03-05 | E-GEOD-59487 | biostudies-arrayexpress
UnknownSafety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial.
Not available
S-EPMC3314794 | biostudies-literature
UnknownEfficacy of liposomal irinotecan + 5-FU/LV vs. S-1 in gemcitabine-refractory metastatic pancreatic cancer: a real-world study using inverse probability of treatment weighting.
Not available
S-EPMC11880175 | biostudies-literature
ProteomicsHuman prion disease iTRAQ
Human prion diseases are fatal neurodegenerative disorders characterized by neuronal damage in brain. Protein S-nitrosylation, the covalent adduction of a NO to cysteine, plays a role in human brain biology, and brain dysfunction is a prominent feature of pPrion disease, yet the direct brain targets...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080756 | MassIVE
TranscriptomicsRabbit heart gene expression in Left ventricle (LV) following banding of the descending thoracic aorta (AOB-LV) vs Sham-control LV and in Right ventricle (RV) following banding the pulmonary artery (PAB-RV) vs. Sham-control RV
Background: Right ventricular (RV) and left ventricular (LV) myocardium differ in their response to pressure-overload hypertrophy (POH). In this report we use microarray and proteomic analyses to identify pathways modulated by LV-, and RV-POH in the immature heart. Methods: Newborn New Zealand White...
ORGANISM(S): Oryctolagus cuniculus 
2011-06-24 | E-GEOD-30194 | biostudies-arrayexpress
ProteomicsHuman cardiac tissue (Apex, LV, RV), whole and isolated cardiomyocyte, processed by s-trap, with and without high pH fractionation, DDA and DIA
Human cardiac tissue (Apex, LV, RV), whole tissue and isolated cardiomyocyte, processed by s-trap, with and without high pH fractionation, DDA of non-fractionated and fractionated and DIA of non-fractionated
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-25 | MSV000087095 | MassIVE
ProteomicsIdentification of the E3 ligase(s) recruited by 955 to degrade CDK9
PROTACs induce the degradation of target proteins by hijacking an E3 ligase. However, it is usually difficult to directly identify the E3 ligase recruited by a new E3 ligase ligand in a PROTAC using the co-immunoprecipitation method because the formation of the complex is transient and very dynamic....
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039401 | Pride
Turboid Protac Pl Cdk9 E3 ligase 
ProteomicsGlobal quantification of glutathione S-transferases in human serum using LC-MS/MS coupled with affinity enrichment
The concentrations of glutathione S-transferases (GSTs) in serum are considered disease biomarkers. Members of the GST superfamily often exhibit functional overlap, and can compensate for each other. Global and quantitative evaluation of serum GSTs is therefore urgent, but we currently lack an effic...
ORGANISM(S): Homo Sapiens 
2022-01-19 | PXD031061 |
UnknownS. aureus Colonization, Biofilm Production, and Phage Susceptibility in Peritoneal Dialysis Patients.
Not available
S-EPMC7558627 | biostudies-literature
Unknown7-[(3-Chloro-6-methyl-6,11-dihydro-dibenzo[c,f][1,2]thia-zepin-11-yl)amino]-hepta-noic acid S,S-dioxide hydro-chloride.
Not available
S-EPMC3515238 | biostudies-literature
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