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ProteomicsIgG M-protein quantification by PRM in blood of multiple myeloma patient
The amino acid sequence of the M-protein for multiple myeloma is unique compared to the polyclonal antibodies in patients’ blood. This uniqueness is exploited to develop an ultra-sensitive M-protein detection method utilizing mass spectrometry (MS). The method involves the de novo amino acid sequenc...
ORGANISM(S): Homo Sapiens 
2021-07-26 | PXD022980 | panorama
GenomicsInonotus hispidus strain:MA | isolate:Inonotus hispidus parasitized on M. alba.Linn
Inonotus hispidus strain:MA | isolate:Inonotus hispidus parasitized on M. alba.Linn Genome sequencing and assembly
PRJNA973857 | ENA
TranscriptomicsComparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum during infection on different insects
We used RNA-Seq to compare transcriptional responses of M. anisopliae and M. acridum to infection of the optically clear hind wings of adult locusts and cockroaches. It was calculated that >82% of predicted M. anisopliae genes and >88% of predicted M. acridum genes were expressed during pre-penetrat...
ORGANISM(S): Metarhizium acridum 
2011-01-31 | E-GEOD-24938 | biostudies-arrayexpress
ProteomicsMass spectrometry provides a highly sensitive non-invasive means of sequencing and tracking M-protein levels in blood of multiple myeloma patients
De nove sequencing of NISTmAb and of an M-protein from an multiple myeloma patient, MM2232
ORGANISM(S): Homo sapiens (Human) 
2021-07-16 | PXD022784 | Pride
Multiple myeloma M-protein 
ProteomicsDirect lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly
M is the most abundant structural membrane protein in coronaviruses and is essential for the formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, Mshort and Mlong, and regulated transition between states is hypothesized to coordinate viral assembly and budding. However, th...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2026-07-09 | PXD079401 | Pride
Hdxms Sars-cov-2 Lipid interaction 
ProteomicsThe M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division
Oocytes are held in meiotic prophase for prolonged periods until hormonal signals trigger meiotic divisions. Key players of M-phase entry are the opposing Cdk1 kinase and PP2AB55δ phosphatase. In Xenopus, the protein Arpp19, phosphorylated at serine 67 by Greatwall, plays an essential role in inhibi...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2021-03-12 | PXD022739 | Pride
M-phase Meiotic Xenopus Oocyte Pp2a Phosphatase Phosphorylation B55 Arpp19 
TranscriptomicsTranscriptional profiling of human macrophages differentiated with macrophage colony-stimulating factor (M-CSF) and/or granulocyte-macrophage colony-stimulating factor (GM-CSF)
In this study, we compared human monocytes differentiated for 7 days with M-CSF and/or GM-CSF. A comparison of the different macrophage populations was made using microarray profiling. Threshold: 1.0 . Logbase: 2 . Technology: Agilent.SingleColor.14850. Normalization: Shift to 75 percentile . Baseli...
ORGANISM(S): Homo sapiens 
2012-03-20 | E-MTAB-791 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of murine bone marrow-derived macrophages differentiated with macrophage colony-stimulating factor (M-CSF) and/or granulocyte-macrophage colony-stimulating factor (GM-CSF) for short term
In this study, we compared murine bone marrow monocytes differentiated for 7 days with M-CSF then BMM were cultured in the absence of M-CSF for 24hr (starved), then treated with different combinations of M-CSF, GM-CSF, TNF and Dex for 16hr. A comparison of the different macrophage populations was ma...
ORGANISM(S): Mus musculus 
2012-03-20 | E-MTAB-792 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of murine bone marrow derived macrophages differentiated with macrophage colony-stimuating factor (M-CSF) or granulocyte-macrophage colony-stimulating factor (GM-CSF)
In this study, we compared murine bone marrow monocytes differentiated for 7 days with M-CSF or GM-CSF. A comparison of the different macrophage populations was made using microarray profiling. Threshold: 1.0 . Logbase: 2 . Technology: Agilent.SingleColor.14868. Normalization: Shift to 75 percentile...
ORGANISM(S): Mus musculus 
2012-03-20 | E-MTAB-790 | biostudies-arrayexpress
TranscriptomicsAntagonism between glucocorticoid and both GM-CSF and M-CSF
In this study, we compared human monocytes treated with GM-CSF, M-CSF, dexamethosone or in combination with dexamethasone. A comparison of the different monocyte populations was made using microarray profiling.
ORGANISM(S): Homo sapiens 
2014-05-01 | E-MTAB-2212 | biostudies-arrayexpress
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