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MetabolomicsMetabolomics study of different tissues of mume 'Longyan' plant grafted on mume rootstock and peach rootstock (Leaf)

Background: Grafting with the dwarf rootstock is an efficient method to control the plant height in fruit production. However, the molecular mechanism is still unclear. Our previous study showed that the plants with Prunus mume rootstock exhibit a considerable reduction in plant height, internode...

2024-08-12 | MTBLS10083 | MetaboLights
MetabolomicsMetabolomics study of different tissues of mume 'Longyan' plant grafted on mume rootstock and peach rootstock (Stem)

Background: Grafting with the dwarf rootstock is an efficient method to control the plant height in fruit production. However, the molecular mechanism is still unclear. Our previous study showed that the plants with Prunus mume rootstock exhibit a considerable reduction in plant height, internode...

2024-08-12 | MTBLS10062 | MetaboLights
MetabolomicsMetabolomics study of different tissues of mume 'Longyan' plant grafted on mume rootstock and peach rootstock (Root)

Background: Grafting with the dwarf rootstock is an efficient method to control the plant height in fruit production. However, the molecular mechanism is still unclear. Our previous study showed that the plants with Prunus mume rootstock exhibit a considerable reduction in plant height, internode...

2024-08-12 | MTBLS10051 | MetaboLights
TranscriptomicsIdentification of miRNAs and Their Target Genes in Peach (Prunus persica L.) Using High-Throughput Sequencing and Degradome Analysis
MicroRNAs play critical roles in various biological and metabolic processes. The function of miRNAs has been widely studied in model plants such as Arabidopsis and rice. However, the number of identified miRNAs and related miRNA targets in peach (Prunus persica) is limited. To understand further the...
ORGANISM(S): Prunus persica 
2014-01-01 | E-GEOD-49579 | biostudies-arrayexpress
ProteomicsBoth wnt signaling and epidermal stem cell-derived exosomes are involved in epidermal development
Millions suffer from skin diseases. Functional epidermal stem cells are needed in skin therapy or drug screening in vitro. We obtained functional epidermal stem cells with intact stemness and cell junctions by treating them with wnt3a. Moreover, epidermal stem cell-derived exosomes were useful in ep...
ORGANISM(S): Homo Sapiens 
2020-07-14 | PXD020351 |
ProteomicsQuantitative proteomics combine with affinity MS revealed the molecular mechanism of ginsenoside anti-tumor effects
The Tandem Mass Tag (TMT) labeling quantitative proteomics technique acquired 55620 MS/MS spectra that identified 5499 proteins and 3045 modified proteins. Of these identified proteins, 224 differentially expressed proteins and modified proteins were significantly altered in non-small cell lung canc...
ORGANISM(S): Homo Sapiens 
2019-02-17 | PXD020149 |
ProteomicsIntegrated Proteomics Characterization of SARS-CoV-2 Associated Liver Injury
The high incidence of liver injury in patients with COVID-19 and the need for long-term medication for recovery make it imperative to study the infectivity and pathogenicity of SARS-CoV-2 in the liver. Here, we have identified significant proteomic changes for the first time in the liver of patients...
ORGANISM(S): Homo Sapiens 
2020-06-23 | PXD019968 |
ProteomicsThe Matrisome Reveals the Characterization of Skin Keloid Microenvironment
Keloids are fibroproliferative dermal tumors of unknown origin that are characterized by the overabundant accumulation of extracellular matrix (ECM) components. The mechanism of keloid formation has remained unclear because of a poor understanding of its molecular basis. In this study, the dermal EC...
ORGANISM(S): Homo Sapiens 
2020-05-08 | PXD019052 |
ProteomicsSARS-CoV-2-Infected hiPSC-Derived Cardiomyocytes Reveal Dynamic Changes in the COVID-19 Hearts
The ongoing coronavirus disease 2019 (COVID-19) pandemic has had an enormous impact on our societies. Moreover, the disease’s extensive and sustained symptoms are now becoming a nonnegligible medical challenge. In this respect, data show that heart failure is one of the most common readmission diagn...
ORGANISM(S): Homo Sapiens 
2023-12-01 | PXD047427 |
ProteomicsSpatially region resolved proteomic map reveals extracellular matrix regulates epidermal growth and function as epidermal stem cell niche
Spatial proteins expression is critical to identify exactly protein localization and function in tissues. By combining decellularization, laser-capture microdissection, and mass spectrometry, six different partitioned proteins among skin layers of stratum corneum (SC), granular-spinous (GS), basal l...
ORGANISM(S): Homo Sapiens 
2021-07-05 | PXD027093 |
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