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ProteomicsSWATH-MS insights on butyric acid effect on mAbs production and redox homeostasis in CHO cells.
Sodium butyrate (NaBu) is well-known for its capacity to hinder cellular growth and act as a histone deacetylase inhibitor. It is commonly employed in the cultivation of recombinant Chinese hamster ovary (CHO) cell cultures to boost the production of specific proteins, such as antibodies. In this in...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-05-06 | PXD048575 | Pride
Lc-msms Redox Swath-ms Cho cells Mabs production Butyric acid 
ProteomicsDetermination of specificity of the MAbs to Der p 21
For determination of specificity of the MAbs, rDer p 21, thermally denatured rDer p 21 and rMBP-Der p 21 (0.3 mg/mL) were printed. the slides were incubated for 2 h 5 different MAbs (0.5 µg/mL for specificity analysis). Then the slides were incubated for 30 min goat anti-mouse IgG Fc Alexa Fluor® 6...
ORGANISM(S): Mus musculus 
2023-12-25 | E-MTAB-13625 | biostudies-arrayexpress
UnknownSWATH-MS insights on sodium butyrate effect on mAbs production and redox homeostasis in CHO cells.
Not available
S-EPMC11668706 | biostudies-literature
UnknownReproducibility and flexibility of monoclonal antibody production with Nicotiana benthamiana.
Not available
S-EPMC8744878 | biostudies-literature
UnknownHuman IgE mAbs identify major antigens of parasitic worm infection.
Not available
S-EPMC9742163 | biostudies-literature
TranscriptomicsGene array for identifying molecules involved in IL-10 regulation during Th17 polarization
IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. Gene array analysis on Stat6 and T-bet double deficient Th17 cells identified the Th2 transcription factor c-Maf to be synergistically up-regulated by IL-6 plus TGFbeta, and associated with Th17 IL-10 pr...
ORGANISM(S): Mus musculus 
2009-03-03 | E-GEOD-15029 | biostudies-arrayexpress
UnknownCharacterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).
Not available
S-EPMC4966511 | biostudies-literature
UnknownGlycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study.
Not available
S-EPMC3149709 | biostudies-literature
UnknownCapture and display of antibodies secreted by hybridoma cells enables fluorescent on-cell screening.
Not available
S-EPMC6512912 | biostudies-literature
UnknownA novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies.
Not available
S-EPMC5916560 | biostudies-literature
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